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产品信息
H00010267-M01
产品规格
种属反应
Human
宿主/亚型
Mouse
/ IgG2b, kappa
分类
Monoclonal
类型
Antibody
克隆号
1F1
抗原
RAMP1 (NP_005846, 27 a.a. approximately 117 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
偶联物
Unconjugated
形式
Liquid
浓度
0.5 mg/mL
纯化类型
Protein A
保存液
PBS, pH 7.4
内含物
no preservative
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
产品详细信息
Product may be used with Sandwich ELISA (Recombinant protein).
Immunogen sequence: CQEANYGALL RELCLTQFQV DMEAVGETLW CDWGRTIRSY RELADCTWHM AEKLGCFWPN AEVDRFFLAV HGRYFRSCPI SGRAVRDPPG S
靶标信息
The protein encoded by this gene is a member of the RAMP family of single-transmembrane-domain proteins, called receptor (calcitonin) activity modifying proteins (RAMPs). RAMPs are type I transmembrane proteins with an extracellular N terminus and a cytoplasmic C terminus. RAMPs are required to transport calcitonin-receptor-like receptor (CRLR) to the plasma membrane. CRLR, a receptor with seven transmembrane domains, can function as either a calcitonin-gene-related peptide (CGRP) receptor or an adrenomedullin receptor, depending on which members of the RAMP family are expressed. In the presence of this (RAMP1) protein, CRLR functions as a CGRP receptor. The RAMP1 protein is involved in the terminal glycosylation, maturation, and presentation of the CGRP receptor to the cell surface.
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生物信息学
蛋白别名: calcitonin receptor-like receptor activity modifying protein 1; Calcitonin-receptor-like receptor activity-modifying protein 1; CRLR activity-modifying protein 1; MGC38240; receptor (calcitonin) activity modifying protein 1; receptor (G protein-coupled) activity modifying protein 1; Receptor activity-modifying protein 1
基因别名: RAMP1
UniProt ID: (Human) O60894
Entrez Gene ID: (Human) 10267
angiogenesis
calcium ion transport
intracellular protein transport
G-protein coupled receptor signaling pathway
regulation of G-protein coupled receptor protein signaling pathway
protein transport
positive regulation of cAMP biosynthetic process
receptor internalization
positive regulation of protein glycosylation
protein localization to plasma membrane
