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The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
The protein encoded by this gene is a member of the RAMP family of single-transmembrane-domain proteins, called receptor (calcitonin) activity modifying proteins (RAMPs). RAMPs are type I transmembrane proteins with an extracellular N terminus and a cytoplasmic C terminus. RAMPs are required to transport calcitonin-receptor-like receptor (CRLR) to the plasma membrane. CRLR, a receptor with seven transmembrane domains, can function as either a calcitonin-gene-related peptide (CGRP) receptor or an adrenomedullin receptor, depending on which members of the RAMP family are expressed. In the presence of this (RAMP3) protein, CRLR functions as an adrenomedullin receptor.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: calcitonin receptor-like receptor activity modifying protein 3; Calcitonin-receptor-like receptor activity-modifying protein 3; CRLR activity-modifying protein 3; receptor (calcitonin) activity modifying protein 3; receptor activity modifying protein 3; Receptor activity-modifying protein 3; receptor-activity-modifying protein 3
基因别名: AI850306; RAMP3
UniProt ID: (Human) O60896, (Mouse) Q9WUP1, (Rat) Q9JJ73
Entrez Gene ID: (Human) 10268, (Mouse) 56089, (Rat) 56820
分子生物学功能: transmembrane signal receptor