Search Thermo Fisher Scientific
PA1-4995 detects RanBP2 from human samples.
PA1-4995 has been successfully used in Western blot, immunoprecimmunoprecipitationitation, and immunohistochemistry applications.
The PA1-4995 immunogen is synthetic peptide corresponding to residues SKAPKSGFEGMFTKKE, repeated 3 times.
RanBP2 interacts with the small GTP-binding protein Ran and forms a large multiprotein complex involved in many biological processes such as mRNA processing, nuclear transport, cell cycle control and postmitotic nuclear reassembly. The protein is identified by western blotting as an apparent molecular mass of 360 kD. It is involved in nucleation of microtubule and control of cell growth by interacting with many protein factors.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: 358 kDa nucleoporin; acute necrotizing encephalopathy 1 (autosomal dominant); E3 SUMO-protein ligase RanBP2; Nuclear pore complex protein Nup358; nucleoporin 358; Nucleoporin Nup358; P270; Ran-binding protein 2; RanBP2; RBP2; transformation-related protein 2
基因别名: A430087B05Rik; ADANE; AI256741; ANE1; IIAE3; NUP358; RANBP2; RGD1560047; TRP1; TRP2
UniProt ID: (Human) P49792, (Mouse) Q9ERU9
Entrez Gene ID: (Human) 5903, (Rat) 294429, (Mouse) 19386
分子生物学功能:
scaffold/adaptor protein
chaperone
transporter