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产品信息
PA5-88927
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant fusion protein containing a sequence corresponding to amino acids 35-357 of human LRPAP1 (NP_0023281)
偶联物
形式
Liquid
浓度
0.83 mg/mL
纯化类型
Affinity Chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.01% thimerosal
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Wet ice
RRID
AB_2805227
产品详细信息
Immunogen sequence: YSREKNQPKP SPKRESGEEF RMEKLNQLWE KAQRLHLPPV RLAELHADLK IQERDELAWK KLKLDGLDED GEKEARLIRN LNVILAKYGL DGKKDARQVT SNSLSGTQED GLDDPRLEKL WHKAKTSGKF SGEELDKLWR EFLHHKEKVH EYNVLLETLS RTEEIHENVI SPSDLSDIKG SVLHSRHTEL KEKLRSINQG LDRLRRVSHQ GYSTEAEFEE PRVIDLWDLA QSANLTDKEL EAFREELKHF EAKIEKHNHY QKQLEIAHEK LRHAESVGDG ERVSRSREKH ALLEGRTKEL GYTVKKHLQD LSGRISRARH NEL; Positive Samples: 293T, HeLa, A-375; Cellular Location: Cell surface, Cytoplasm, Endoplasmic reticulum
靶标信息
Interacts with LRP1/alpha-2-macroglobulin receptor and glycoprotein 330.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: 39 kDa receptor-associated protein; Alpha-2-macroglobulin receptor-associated protein; Alpha-2-macroglobulin receptor-associated protein precursor (Alpha-2-MRAP) (Low density lipoprotein receptor-related protein-associated protein 1) (RAP) (Heparin binding protein-44) (HBP-44); Alpha-2-MRAP; Gp330-binding 45 kDa protein; HBP-44; Heparin-binding protein 44; low density lipoprotein receptor related protein, associated protein 1; low density lipoprotein receptor-related protein associated protein 1; Low density lipoprotein receptor-related protein-associated protein 1; low density lipoprotein-related protein-associated protein 1 (alpha-2-macroglobulin receptor-associated protein 1); RAP
基因别名: A2MRAP; A2RAP; AA617339; AI790446; alpha-2-MRAP; AU042172; C77774; HBP44; LRPAP1; MRAP; MYP23; RAP
UniProt ID: (Human) P30533, (Rat) Q99068, (Mouse) P55302
Entrez Gene ID: (Human) 4043, (Rat) 116565, (Mouse) 16976
protein folding
receptor-mediated endocytosis
negative regulation of very-low-density lipoprotein particle clearance
vesicle-mediated transport
negative regulation of protein binding
extracellular negative regulation of signal transduction
negative regulation of beta-amyloid clearance
negative regulation of receptor activity
