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RASSF2 Antibody (PA5-90687) in WB
Western blot analysis of RASSF2 in extracts of Raji cells. Samples were incubated with RASSF2 Polyclonal antibody (Product # PA5-90687) using a dilution of 1:1,000, followed by HRP Goat Anti-Rabbit IgG (H+L) at a dilution of 1:10,000. Lysates/proteins: 25 µg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Enhanced Kit. Exposure time: 1s.
产品信息
PA5-90687
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant fusion protein containing a sequence corresponding to amino acids 70-160 of human RASSF2 (NP_0555521)
偶联物
形式
Liquid
浓度
0.5 mg/mL
纯化类型
Affinity Chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.01% thimerosal
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Wet ice
RRID
AB_2806176
产品详细信息
Immunogen sequence: MQDDNERIRP PPSSSSWHSG CNLGAQGTTL KPLTVPKVQI SEVDAPPEGD QMPSSTDSRG LKPLQEDTPQ LMRTRSDVGV RRRGNVRTPS D; Positive Samples: Raji; Cellular Location: Cytoplasm, Nucleus
靶标信息
Potential tumor suppressor. Acts as a KRAS-specific effector protein. May promote apoptosis and cell cycle arrest. Stabilizes STK3/MST2 by protecting it from proteasomal degradation.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: centromere protein 34; Ras association (RalGDS/AF-6) domain family 2; Ras association (RalGDS/AF-6) domain family member 2; Ras association domain-containing protein 2; RP4-599I11.1
基因别名: CENP-34; KIAA0168; RASFADIN; RASSF2
UniProt ID: (Human) A6NIX9
Entrez Gene ID: (Human) 9770
skeletal system development
ossification
protein phosphorylation
cell cycle
positive regulation of protein autophosphorylation
negative regulation of peptidyl-serine phosphorylation
epidermal growth factor receptor signaling pathway via I-kappaB kinase/NF-kappaB cascade
positive regulation of apoptotic process
regulation of osteoblast differentiation
regulation of osteoclast differentiation
positive regulation of protein kinase activity
positive regulation of JNK cascade
bone remodeling
homeostasis of number of cells
protein stabilization
negative regulation of NIK/NF-kappaB signaling
