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RASSF2 Antibody (MA5-24746) in WB
Western blot analysis of RASSF2 in Raji whole cell lysate. Samples were incubated with RASSF2 monoclonal antibody (Product # MA5-24746) using a dilution of 1:2,000 followed by Goat Anti-mouse IgG, (H+L), Peroxidase conjugated at a dilution of 1:10,000. Lysates/proteins: 20 µg per lane. Predicted band size: 38 kDa. Blocking/Dilution buffer: 5% NFDM/TBST.
产品信息
MA5-24746
产品规格
种属反应
Human
宿主/亚型
Mouse
/ IgG2a, kappa
分类
Monoclonal
类型
Antibody
克隆号
1509CT269.10.9.29
抗原
Recombinant protein between 1-326 amino acids from human RASSF2
偶联物
形式
Liquid
浓度
1.46 mg/mL
纯化类型
Protein G
保存液
PBS, pH 7.4
内含物
0.09% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
AB_2717221
靶标信息
Potential tumor suppressor. Acts as a KRAS-specific effector protein. May promote apoptosis and cell cycle arrest. Stabilizes STK3/MST2 by protecting it from proteasomal degradation.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: centromere protein 34; Ras association (RalGDS/AF-6) domain family 2; Ras association (RalGDS/AF-6) domain family member 2; Ras association domain-containing protein 2; RP4-599I11.1
基因别名: CENP-34; KIAA0168; RASFADIN; RASSF2
UniProt ID: (Human) A6NIX9
Entrez Gene ID: (Human) 9770
skeletal system development
ossification
protein phosphorylation
cell cycle
positive regulation of protein autophosphorylation
negative regulation of peptidyl-serine phosphorylation
epidermal growth factor receptor signaling pathway via I-kappaB kinase/NF-kappaB cascade
positive regulation of apoptotic process
regulation of osteoblast differentiation
regulation of osteoclast differentiation
positive regulation of protein kinase activity
positive regulation of JNK cascade
bone remodeling
homeostasis of number of cells
protein stabilization
negative regulation of NIK/NF-kappaB signaling
