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产品信息
H00005930-M01
应用
建议稀释比
已发表文章
产品规格
种属反应
Human
宿主/亚型
Mouse
/ IgG1, kappa
分类
Monoclonal
类型
Antibody
克隆号
5A11
抗原
RBBP6 (NP_008841, 1582 a.a. approximately 1691 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
偶联物
形式
Liquid
浓度
0.34 mg/mL
纯化类型
Protein A
保存液
PBS, pH 7.4
内含物
no preservative
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Wet ice
产品详细信息
Immunogen sequence: SSGNKLLYIL NPPETQVEKE QITGQIDKST VKPKPQLSHS SRLSSDLTRE TDEAAFEPDY NESDSESNVS VKEEESSGNI SKDLKDKIVE KAKESLDTAA VVQVGISRNQ
靶标信息
This gene encodes a cilia-associated protein belonging to the kinesin family. This protein plays a role in the sonic hedgehog (SHH) signaling pathway through the regulation of GLI transcription factors. It functions as a negative regulator of the SHH pathway by preventing inappropriate activation of GLI2 in the absence of ligand, and as a positive regulator by preventing the processing of GLI3 into its repressor form. Mutations in this gene have been associated with various ciliopathies.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: E3 ubiquitin-protein ligase RBBP6; p53-associated cellular protein of testis; Proliferation potential-related protein; Protein P2P-R; RB-binding Q-protein 1; RBQ-1; retinoblastoma binding protein 6; Retinoblastoma-binding protein 6; retinoblastoma-binding protein 6, isoform 3; Retinoblastoma-binding Q protein 1; RING-type E3 ubiquitin transferase RBBP6
基因别名: MY038; P2P-R; P2PR; PACT; RBBP6; RBQ-1; RBQ1; SNAMA
UniProt ID: (Human) Q7Z6E9
Entrez Gene ID: (Human) 5930
protein polyubiquitination
in utero embryonic development
DNA replication
regulation of DNA replication
mRNA processing
cellular response to DNA damage stimulus
multicellular organism growth
protein ubiquitination involved in ubiquitin-dependent protein catabolic process
embryonic organ development
somite development
