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Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol. Western blot detects a band of approximately 21 kDa (predicted molecular weight: 21 kDa).
This gene encodes a protein with a conserved RNA-binding motif. The protein is found predominantly in the nucleus, although it is also present in the cytoplasm. It is preferentially associated with mRNAs produced by splicing, including both nuclear mRNAs and newly exported cytoplasmic mRNAs. It is thought that the protein remains associated with spliced mRNAs as a tag to indicate where introns had been present, thus coupling pre- and post-mRNA splicing events. Previously, it was thought that two genes encode this protein, RBM8A and RBM8B; it is now thought that the RBM8B locus is a pseudogene. Two alternative start codons result in two forms of the protein, and this gene also uses multiple polyadenylation sites.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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蛋白别名: Binder of OVCA1-1; BOV-1; BOV1; BOV1A; BOV1B; BOV1C; ribonucleoprotein RBM8; Ribonucleoprotein RBM8A; Ribonucleoprotein RBM8A-A; RNA binding motif protein 8B; rna-binding; RNA-binding motif protein 8A; RNA-binding motif protein 8A-A; RNA-binding protein 8A; RNA-binding protein 8A-A; RNA-binding protein Y14
基因别名: BOV-1A; BOV-1B; BOV-1C; C1DELq21.1; DEL1q21.1; HSPC114; MDS014; RBM8; rbm8-A; RBM8A; rbm8a-A; rbm8a-b; RBM8B; TAR; tsunagi; XELAEV_18042903mg; Y14; ZNRP; ZRNP1
UniProt ID: (Human) Q9Y5S9, (Xenopus) Q9DF42
Entrez Gene ID: (Human) 9939, (Xenopus) 399167