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产品信息
MA5-46797
产品规格
种属反应
Mouse
宿主/亚型
Rabbit
/ IgG
Expression System
HEK293 cells
分类
Recombinant Monoclonal
类型
Antibody
克隆号
008
抗原
Recombinant protein encoding Mouse RBP4 (Met1-Leu201).
偶联物
激发/发射光谱
498/517 nm
查看光谱
形式
Liquid
浓度
100 µg/mL
纯化类型
Protein A
保存液
PBS with 0.5% BSA
内含物
0.03% ProClin 300
保存条件
4° C, store in dark, DO NOT FREEZE!
运输条件
Ambient (domestic); Wet ice (international)
RRID
AB_2937869
产品详细信息
Preparation: This antibody was obtained from a rabbit immunized with purified, recombinant Mouse RBP4 (Met1-Leu201) and conjugated with FITC under optimum conditions, the unreacted FITC was removed.
Storage: This antibody can be stored at 2C-8C for twelve months without detectable loss of activity. Protected from prolonged exposure to light. Do not freeze! Sodium azide is toxic to cells and should be disposed of properly. Flush with large volumes of water during disposal.
靶标信息
This protein belongs to the lipocalin family and is the specific carrier for retinol in the blood. It delivers retinol from the liver stores to the peripheral tissues. In plasma, the RBP-retinol complex interacts with transthyretin which prevents its loss by filtration through the kidney glomeruli. A deficiency of vitamin A blocks secretion of the binding protein post translationally and results in defective delivery and supply to the epidermal cells.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Plasma retinol binding protein 4 (PRBP); Plasma retinol-binding protein; PRBP; RBP; retinol; retinol binding; Retinol binding protein 4 interstitial; retinol binding protein 4, cellular; Retinol-binding protein 4
基因别名: Rbp-4; Rbp4
UniProt ID: (Mouse) Q00724
Entrez Gene ID: (Mouse) 19662
eye development
gluconeogenesis
transport
spermatogenesis
heart development
male gonad development
embryo development
maintenance of gastrointestinal epithelium
lung development
positive regulation of insulin secretion
response to retinoic acid
response to insulin
retinol transport
retinol metabolic process
retinal metabolic process
glucose homeostasis
embryonic organ morphogenesis
embryonic skeletal system development
cardiac muscle tissue development
female genitalia morphogenesis
detection of light stimulus involved in visual perception
positive regulation of immunoglobulin secretion
vitamin transport
retina development in camera-type eye
negative regulation of cardiac muscle cell proliferation
embryonic retina morphogenesis in camera-type eye
uterus development
vagina development
urinary bladder development
heart trabecula formation
