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RBP4/Retinol Binding Protein 4 Antibody (5950-MSM14-P1) in IHC (P)
Immunohistochemistry analysis of formalin-fixed, paraffin-embedded feline kidney stained with RBP4/Retinol Binding Protein 4 Monoclonal Antibody (Product # 5950-MSM14-P1) at a dilution of 2 µg/mL. HIER: Tris/EDTA, pH9.0, 45 min. 2 °C: HRP-polymer, 30 min. DAB, 5 min.
产品信息
5950-MSM14-P1
产品规格
种属反应
Dog,
Cat,
Human
宿主/亚型
Mouse
/ IgG2b, kappa
分类
Monoclonal
类型
Antibody
克隆号
RBP4, 4314
抗原
Recombinant fragment (around aa29-148) of human RBP4 protein
偶联物
形式
Liquid
浓度
200 µg/mL
纯化类型
Protein A/G
保存液
PBS, pH 7.4, with 0.05% BSA
内含物
0.05% sodium azide
保存条件
4° C
运输条件
Ambient (domestic); Wet ice (international)
产品详细信息
Immunohistochemistry (PFA fixed): incubate antibody for 30 min RT. Staining of formalin-fixed tissues requires heating tissue sections in 10mM Tris with 1mM EDTA, pH 9.0, for 45 min at 95 degrees C followed by cooling at RT for 20 minutes.
靶标信息
This protein belongs to the lipocalin family and is the specific carrier for retinol in the blood. It delivers retinol from the liver stores to the peripheral tissues. In plasma, the RBP-retinol complex interacts with transthyretin which prevents its loss by filtration through the kidney glomeruli. A deficiency of vitamin A blocks secretion of the binding protein post translationally and results in defective delivery and supply to the epidermal cells.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Plasma retinol binding protein 4 (PRBP); Plasma retinol-binding protein; PRBP; RBP; retinol; retinol binding; Retinol binding protein 4 interstitial; retinol binding protein 4, plasma; Retinol-binding protein 4; retinol-binding protein 4, interstitial
基因别名: MCOPCB10; PRO2222; RBP4; RDCCAS
UniProt ID: (Human) P02753
Entrez Gene ID: (Human) 5950, (Dog) 477775
retinoid metabolic process
eye development
gluconeogenesis
heart development
visual perception
maintenance of gastrointestinal epithelium
lung development
positive regulation of insulin secretion
response to retinoic acid
retinol transport
retinol metabolic process
glucose homeostasis
response to ethanol
embryonic organ morphogenesis
embryonic skeletal system development
cardiac muscle tissue development
female genitalia morphogenesis
positive regulation of immunoglobulin secretion
negative regulation of cardiac muscle cell proliferation
embryonic retina morphogenesis in camera-type eye
uterus development
vagina development
urinary bladder development
heart trabecula formation
