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Adding 0.2 mL of distilled water will yield a concentration of 500 µg/mL.
PHB2 acts as a mediator of transcriptional repression by nuclear hormone receptors via recruitment of histone deacetylases. This protein functions as an estrogen receptor (ER)-selective coregulator that potentiates the inhibitory activities of antiestrogens and represses the activity of estrogens. It competes with NCOA1 for modulation of ER transcriptional activity. It is probably involved in regulating mitochondrial respiration activity and in aging.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: B-cell associated protein; B-cell receptor associated protein 37; B-cell receptor-associated protein 37; B-cell receptor-associated protein BAP37; BAP-37; D-prohibitin; MGC117268; PHB2; phb2 {ECO:0000250|UniProtKB:Q99623}; Prohibitin-2; Repressor of estrogen receptor activity
基因别名: AU044498; BAP; Bap-37; Bap37; Bcap27; BCAP37; hBAP; p22; PHB2; PNAS-141; REA
UniProt ID: (Human) Q99623, (Mouse) O35129, (Rat) Q5XIH7
Entrez Gene ID: (Human) 11331, (Mouse) 12034, (Rat) 114766