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RECK Antibody (MA5-14781) in WB
Western blot analysis of RECK in extracts from 3T3L1 and NIH/3T3 cell lines using RECK monoclonal antibody (Product # MA5-14781).
产品信息
MA5-14781
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse,
Non-human primate,
Rat
已发表种属
Human
宿主/亚型
Rabbit
/ IgG
分类
Monoclonal
类型
Antibody
克隆号
F.286.6
抗原
Synthetic peptide corresponding to residues surrounding Ile913 of human RECK protein
偶联物
Unconjugated
形式
Liquid
浓度
513 µg/mL
纯化类型
Affinity chromatography
保存液
0.01M HEPES, pH 7.5, with 0.15M NaCl, 100µg/mL BSA, 50% glycerol
内含物
<0.02% sodium azide
保存条件
-20°C
运输条件
Ambient (domestic); Wet ice (international)
RRID
AB_11005172
产品详细信息
It is not recommended to aliquot this antibody.
靶标信息
RECK is a cysteine-rich, extracellular protein with protease inhibitor-like domains whose expression is suppressed strongly in many tumors and cells transformed by various kinds of oncogenes. In normal cells, this membrane-anchored glycoprotein may serve as a negative regulator for matrix metalloproteinase-9, a key enzyme involved in tumor invasion and metastasis.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: hRECK; membrane-anchored glycoprotein (metastasis and invasion); membrane-anchored glycoprotein RECK; mRECK; Reversion-inducing cysteine-rich protein with Kazal motifs; Reversion-inducing cysteine-rich protein with Kazal motifs precursor (mRECK); reversion-inducing-cysteine-rich protein with kazal motifs; suppression of tumorigenicity 15; suppression of tumorigenicity 15 (reversion-inducing-cysteine-rich protein with kazal motifs); suppression of tumorigenicity 5 (reversion-inducing-cysteine-rich protein with kazal motifs); Suppressor of tumorigenicity 15 protein
基因别名: mRECK; RECK; ST15
UniProt ID: (Human) O95980, (Mouse) Q9Z0J1
Entrez Gene ID: (Human) 8434, (Mouse) 53614, (Rat) 313488
blood vessel maturation
embryo implantation
extracellular matrix organization
negative regulation of cell migration
embryonic forelimb morphogenesis
negative regulation of metalloendopeptidase activity
negative regulation of peptidase activity
negative regulation of endopeptidase activity
positive regulation of Notch signaling pathway
