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Immunogen sequence: DIIMRPSCAP GWFYHKSNCY GYFRKLRNWS DAELECQSYG NGAHLASILS LKEASTIAEY ISGYQRSQPI WIGLHDPQKR QQWQWIDGAM YLYRSWSGKS MGGNKHCAEM SSNNNFLTWS SNECNKRQHF LCKYRP; Positive Samples: Mouse stomach, Rat stomach
Reg IV is part of the regenerating gene family within the C-type lectin superfamily. This family is involved in liver, pancreatic, gastric and intestinal cell proliferation and differentiation. Reg IV is a 158-amino acid secretory protein implicated in cell regeneration and/or survival with a definite growth stimulating effect on pancreatic beta cells. It is highly expressed in colorectal, gastric, prostate and other types of cancer. Reg IV-positive tumor cells display different phenotypes including mucus-secreting, enterocyte-like, and undifferentiated.
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仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: GISPREG-4; REG-4; Regenerating islet-derived protein 4
基因别名: 2010002L15Rik; GISP; Reg4; RELP
UniProt ID: (Mouse) Q9D8G5, (Rat) Q68AX7
Entrez Gene ID: (Mouse) 67709, (Rat) 445583