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This antibody detects endogenous protein at a molecular weight of 63 kDa.
Purity is >95% by SDS-PAGE.
Raftlin, also known as RFTN1 (raftlin, lipid raft linker 1), cell migration-inducing gene 2 protein, PIB10, PIG9 or MIG2, is a 578 amino acid cell membrane protein and lipid anchor that is essential for raft cell assembly and maintenance. A member of the raftlin family, Raftlin modulates B-cell antigen receptor-mediated signaling, TCR signals, and is involved in T cell-mediated immune responses. The gene encoding Raftlin maps to human chromosome 3, which houses over 1,100 genes, including a chemokine receptor (CKR) gene cluster and a variety of human cancer-related gene loci. Key tumor suppressing genes on chromosome 3 include those that encode the apoptosis mediator RASSF1, the cell migration regulator HYAL1 and the angiogenesis suppressor SEMA3B. Marfan Syndrome, porphyria, von Hippel-Lindau syndrome, osteogenesis imperfecta and Charcot-Marie-Tooth Disease are a few of the numerous genetic diseases associated with chromosome 3.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Cell migration-inducing gene 2 protein; proliferation-inducing protein 10; proliferation-inducing protein 9; Raft-linking protein; Raftlin
基因别名: 2310015N21Rik; AI853526; KIAA0084; MIG2; PIB10; PIG9; RAFTLIN; RFTN1; RGD1310777; RGD1563347
UniProt ID: (Human) Q14699, (Mouse) Q6A0D4
Entrez Gene ID: (Human) 23180, (Rat) 501095, (Mouse) 76438