Invitrogen

RGN Monoclonal Antibody (4B9)

查看其他8个Regucalcin抗体

抗体检测数据 (3)

RGN Antibody in Immunocytochemistry (ICC/IF)

RGN Antibody in Immunocytochemistry (ICC/IF)

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RGN Antibody (MA5-24432) in ICC/IF

Immunofluorescent analysis of RGN in HeLa cell lysates. Samples were probed using a Mouse Monoclonal RGN (4B9) Antibody (Product # MA5-24432) at 15 µg/mL.

RGN Antibody in Immunocytochemistry (ICC/IF)

RGN Antibody in Western Blot (WB)

RGN Antibody in ELISA (ELISA)

Product Image Gallery

RGN Antibody in Immunocytochemistry (ICC/IF) — Immunofluorescent analysis of RGN in HeLa cell lysates. Samples were probed using a Mouse Monoclonal RGN (4B9) Antibody (Product # MA5-24432) at 15 µg/mL.

RGN Antibody in Western Blot (WB) — Western blot analysis of RGN in transfected 293T cell line. Lane 1: RGN transfected lysate (33.3 KDa). Lane 2: Non-transfected lysate. Samples were probed using a Mouse Monoclonal RGN (4B9) Antibody (Product # MA5-24432).

RGN Antibody in ELISA (ELISA) — ELISA analysis using recombinant GST tagged RGN Antibody (Product # MA5-24432) at 3 ng/mL as the capture antibody.

产品信息

MA5-24432

应用

建议稀释比

已发表文章

免疫印迹 (WB)

1-5 µg/mL

-

免疫细胞化学 (ICC/IF)

Assay-Dependent

-

酶联免疫吸附实验 (ELISA)

3 ng/mL

-

产品规格

种属反应

Human

宿主/亚型

Mouse / IgG2a, kappa

分类

Monoclonal

类型

Antibody

克隆号

4B9

抗原

RGN (NP_004674.1, 200 a.a. ~ 299 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

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偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

0.4 mg/mL

纯化类型

Protein A

保存液

PBS, pH 7.4

内含物

no preservative

保存条件

-20° C, Avoid Freeze/Thaw Cycles

运输条件

Ambient (domestic); Wet ice (international)

RRID

AB_2633404

产品详细信息

Peptide Sequence: EQIPDGMCID AEGKLWVACY NGGRVIRLDP VTGKRLQTVK LPVDKTTSCC FGGKNYSEMY VTCARDGMDP EGLLRQPEAG GIFKITGLGV KGIAPYSYAG

靶标信息

The protein encoded by this gene is a highly conserved, calcium-binding protein, that is preferentially expressed in the liver and kidney. It may have an important role in calcium homeostasis. Studies in rat indicate that this protein may also play a role in aging, as it shows age-associated down-regulation. This gene is part of a gene cluster on chromosome Xp11.3-Xp11.23. Alternative splicing results in two transcript variants having different 5' UTRs, but encoding the same protein.

仅用于科研。不用于诊断过程。未经明确授权不得转售。

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引用该产品

生物信息学

蛋白别名: epididymis secretory protein Li 41; Gluconolactonase; GNL; RC; Regucalcin; Senescence marker protein 30; SMP-30

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基因别名: GNL; HEL-S-41; RC; RGN; SMP30

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UniProt ID: (Human) Q15493

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Entrez Gene ID: (Human) 9104

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gluconolactonase activity calcium ion binding zinc ion binding enzyme regulator activity esterase

参与通路

kidney development negative regulation of protein kinase activity cellular calcium ion homeostasis spermatogenesis aging positive regulation of triglyceride biosynthetic process positive regulation of glucose metabolic process positive regulation of phosphatase activity L-ascorbic acid biosynthetic process negative regulation of phosphoprotein phosphatase activity positive regulation of ATPase activity negative regulation of GTPase activity negative regulation of apoptotic process positive regulation of GTPase activity negative regulation of nitric oxide biosynthetic process positive regulation of fatty acid biosynthetic process negative regulation of epithelial cell proliferation regulation of calcium-mediated signaling negative regulation of cyclic-nucleotide phosphodiesterase activity liver regeneration negative regulation of sperm motility positive regulation of superoxide dismutase activity positive regulation of calcium-transporting ATPase activity negative regulation of RNA biosynthetic process negative regulation of bone development positive regulation of proteolysis involved in cellular protein catabolic process negative regulation of calcium-dependent ATPase activity negative regulation of DNA catabolic process positive regulation of dUTP diphosphatase activity negative regulation of leucine-tRNA ligase activity negative regulation of DNA biosynthetic process