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产品信息
H00000389-M01
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Mouse
/ IgG2b, kappa
分类
Monoclonal
类型
Antibody
克隆号
2E12
抗原
RHOC (AAH07245, 1 a.a. approximately 193 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
偶联物
形式
Liquid
浓度
See Label
纯化类型
Affinity chromatography
保存液
PBS, pH 7.4
内含物
no preservative
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
产品详细信息
Sequence of this protein is as follows: MAAIRKKLVI VGDGACGKTC LLIVFSKDQF PEVYVPTVFE NYIADIEVDG KQVELALWDT AGQEDYDRLR PLSYPDTDVI LMCFSIDSPD SLENIPEKWT PEVKHFCPNV PIILVGNKKD LRQDEHTRRE LAKMKQEPVR SEEGRDMANR ISAFGYLECS AKTKEGVREV FEMATRAGLQ VRKNKRRRGC PIL
靶标信息
RhoC is part of blood-group antigens that are generally defined as molecules formed by sequential addition of saccharides to the carbohydrate side chains of lipids and proteins detected on erythrocytes and certain epithelial cells. The A, B and H antigens are reported to undergo modulation during malignant cellular transformation. Blood group related antigens represent a group of carbohydrate determinants carried on both glycolipids and glycoproteins. They are usually mucin-type, and are detected on erythrocytes, certain epithelial cells, and in secretions of certain individuals. Sixteen genetically and biosynthetically distinct but inter-related specificities belong to this group of antigens, including A, B, H, Lewis A, Lewis B, Lewis X, Lewis Y, and precursor type 1 chain antigens.
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生物信息学
蛋白别名: aplysia ras-related homolog 9 (RhoC); AR ARHC; h9; MGC1448; MGC61427; oncogene RHO H9; ras homolog 9 (RhoC); ras homolog gene family, member C; RAS-related homolog 9; Rho; Rho cDNA clone 9; RHO MGC1448; Rho-related GTP-binding protein RhoC; rhoC GTPase; SIG-61; Silica-induced gene 61 protein; small GTP binding protein RhoC
基因别名: AI324259; ARH9; ARHC; H9; RHOC; RHOH9
UniProt ID: (Human) P08134, (Mouse) Q62159
Entrez Gene ID: (Human) 389, (Mouse) 11853, (Rat) 295342
cytokinesis
small GTPase mediated signal transduction
positive regulation of I-kappaB kinase/NF-kappaB signaling
apical junction assembly
wound healing, spreading of cells
regulation of small GTPase mediated signal transduction
positive regulation of lipase activity
skeletal muscle satellite cell migration
signal transduction
