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RPA70 Antibody (MA5-53828) in WB
Western Blot analysis of RPA70. Total cell lysates (30 μg) from various cell lines were loaded and separated by SDS-PAGE. The blot was incubated with RPA70 recombinant monoclonal antibody (Product # MA5-53828) with a dilution of 1:5,000, followed by HRP-conjugated goat anti-rabbit secondary antibody with a dilution of 1:20,000. Image was developed using FeQTM ECL Substrate Kit.
产品信息
MA5-53828
产品规格
种属反应
Human,
Rat
宿主/亚型
Rabbit
/ IgG
Expression System
HEK293F
分类
Recombinant Monoclonal
类型
Antibody
克隆号
23GB4885
抗原
A synthesized peptide derived from human RPA70 (1-54AA).
偶联物
形式
Liquid
纯化类型
Affinity chromatography
保存液
PBS, pH 7.4, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Wet ice (domestic); Dry ice (international)
靶标信息
This gene Plays an essential role in several cellular processes in DNA metabolism including replication, recombination and DNA repair. Binds and subsequently stabilizes single-stranded DNA intermediates and thus prevents complementary DNA from reannealing.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: MSTP075; Replication factor A protein 1; Replication protein A 70 kDa DNA-binding subunit; replication protein A1, 70kDa; RF-A protein 1; RP-A p70; Single-stranded DNA-binding protein
基因别名: Cb1-727; HSSB; MST075; REPA1; RF-A; RP-A; RPA1; RPA70
UniProt ID: (Human) P27694
Entrez Gene ID: (Human) 6117, (Rat) 287524
G1/S transition of mitotic cell cycle
telomere maintenance via recombination
telomere maintenance
double-strand break repair via homologous recombination
DNA replication
DNA-dependent DNA replication
DNA repair
transcription-coupled nucleotide-excision repair
base-excision repair
nucleotide-excision repair
nucleotide-excision repair, preincision complex stabilization
nucleotide-excision repair, preincision complex assembly
nucleotide-excision repair, DNA incision, 3'-to lesion
nucleotide-excision repair, DNA incision, 5'-to lesion
nucleotide-excision repair, DNA gap filling
mismatch repair
DNA recombination
protein sumoylation
translesion synthesis
nucleotide-excision repair, DNA incision
interstrand cross-link repair
error-prone translesion synthesis
DNA damage response, detection of DNA damage
error-free translesion synthesis
regulation of cellular response to heat
regulation of signal transduction by p53 class mediator
in utero embryonic development
meiotic nuclear division
positive regulation of cell proliferation
hemopoiesis
homeostasis of number of cells within a tissue
chromosome organization
