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Immunogen sequence: LRGGAGVGSM TKIYGGRQRN GVMPSHFSRG SKSVARRVLQ ALEGLKMVEK DQDGGRKLTP QGQRDLDRIA GQVAAANKKH
Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 40S subunit. The protein belongs to the S19E family of ribosomal proteins. It is located in the cytoplasm. Mutations in this gene cause Diamond-Blackfan anemia, a constitutional erythroblastopenia characterized by absent or decreased erythroid precursors, in a subset of patients. This suggests a possible extra-ribosomal function for this gene in erythropoietic differentiation and proliferation, in addition to its ribosomal function. Higher expression levels of this gene in some primary colon carcinomas compared to matched normal colon tissues has been observed. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: 40S ribosomal protein S19; HGNC:10402; Small ribosomal subunit protein eS19
基因别名: DBA; DBA1; Dsk3; RPS19; S19
UniProt ID: (Human) P39019, (Rat) P17074, (Mouse) Q9CZX8
Entrez Gene ID: (Human) 6223, (Rat) 29287, (Mouse) 20085