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This Antibody was verified by Knockdown to ensure that the antibody binds to the antigen stated.
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It is not recommended to aliquot this antibody.
RRAGC (Ras-related GTP-binding protein C) is a monomeric guanine nucleotide-binding protein that plays a crucial role in the cellular response to amino acid availability through regulations of the mTORC1 signaling cascade. RRAGC forms a heterodimer with RRAGA and RRAGB and is primarily localized to the cytoplasm. It cycles between an inactive GTP-bound and an active GDP-bound form. RRAGC, in its active form, participates in the re-localization of mTORC1 to the lysosomes and its subsequent activation by the GTPase RHEB. This re-localization is a crucial step in the activation of the TOR signaling cascade by amino acids.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: GTPase-interacting protein 2; Rag C; Rag C protein; Ras-related GTP binding C; Ras-related GTP-binding protein C; RRAGC; small GTPase homolog; small GTPase, homolog; TIB929
基因别名: AU041672; GTR2; RAGC; RRAGC; TIB929; YGR163W
UniProt ID: (Human) Q9HB90, (Mouse) Q99K70
Entrez Gene ID: (Human) 64121, (Mouse) 54170, (Rat) 298514
分子生物学功能: small GTPase