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RRM2 Antibody (PA5-92365) in ICC/IF
Immunofluorescence analysis of RRM2 in U2OS cells. Samples were incubated with RRM2 Polyclonal antibody (Product # PA5-92365) using a dilution of 1:100 (40x lens). Blue: DAPI for nuclear staining.
产品信息
PA5-92365
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse,
Rat
已发表种属
Mouse
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant fusion protein containing a sequence corresponding to amino acids 1-389 of human RRM2 (NP_0010251)
偶联物
Unconjugated
形式
Liquid
浓度
1.51 mg/mL
纯化类型
Affinity Chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
RRID
AB_2806453
产品详细信息
Positive Samples: MCF-7, SW480, HeLa, Jurkat, Mouse thymus; Cellular Location: Cytoplasm
Immunogen sequence: MLSLRVPLAP ITDPQQLQLS PLKGLSLVDK ENTPPALSGT RVLASKTARR IFQEPTEPKT KAAAPGVEDE PLLRENPRRF VIFPIEYHDI WQMYKKAEAS FWTAEEVDLS KDIQHWESLK PEERYFISHV LAFFAASDGI VNENLVERFS QEVQITEARC FYGFQIAMEN IHSEMYSLLI DTYIKDPKER EFLFNAIETM PCVKKKADWA LRWIGDKEAT YGERVVAFAA VEGIFFSGSF ASIFWLKKRG LMPGLTFSNE LISRDEGLHC DFACLMFKHL VHKPSEERVR EIIINAVRIE QEFLTEALPV KLIGMNCTLM KQYIEFVADR LMLELGFSKV FRVENPFDFM ENISLEGKTN FFEKRVGEYQ RMGVMSSPTE NSFTLDADF
靶标信息
RRM2 is one of two non-identical subunits for ribonucleotide reductase. This reductase catalyzes the formation of deoxyribonucleotides from ribonucleotides. Synthesis of the protein (M2) is regulated in a cell-cycle dependent fashion.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: ribonucleoside-diphosphate reductase M2 chain; Ribonucleoside-diphosphate reductase subunit M2; Ribonucleotide reductase 2; ribonucleotide reductase M2 polypeptide; Ribonucleotide reductase small chain; Ribonucleotide reductase small subunit; RRR2M
基因别名: AA407299; R2; RR2; RR2M; RRM2
UniProt ID: (Human) P31350, (Mouse) P11157, (Rat) Q4KLN6
Entrez Gene ID: (Human) 6241, (Mouse) 20135, (Rat) 362720
G1/S transition of mitotic cell cycle
regulation of transcription involved in G1/S transition of mitotic cell cycle
DNA replication
deoxyribonucleoside diphosphate metabolic process
deoxyribonucleotide biosynthetic process
nucleobase-containing small molecule interconversion
protein heterotetramerization
oxidation-reduction process
deoxyribonucleotide metabolic process
protein oligomerization
mitotic cell cycle
pyrimidine nucleobase metabolic process
positive regulation of cell proliferation
