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Predicted to react with Mouse samples.
RSF1 is required for assembly of regular nucleosome arrays by the RSF chromatin remodelling complex. Rsf1 facilitates transcription of hepatitis B virus (HBV) genes by the pX transcription activator. In case of infection by HBV, together with pX, it represses TNF-alpha induced NF-kappaB transcription activation. Rsf1 represses transcription when artificially recruited to chromatin by fusion to a heterogeneous DNA binding domain. Rsf1 interacts with SMARCA5/SNF2H to form the RSF complex and also binds the HBV pX/HBx protein, which is required to activate transcription of the viral genome.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: HBV pX associated protein-8; HBV pX-associated protein 8; hepatitis B virus x associated protein; Hepatitis B virus X-associated protein; p325 subunit of RSF chromatin-remodeling complex; Remodeling and spacing factor 1; Rsf-1
基因别名: 4832420A03Rik; C030033M12Rik; Gm164; HBXAP; p325; RSF-1; RSF1; XAP8
UniProt ID: (Human) Q96T23
Entrez Gene ID: (Human) 51773, (Mouse) 233532