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产品信息
MA5-47608
产品规格
种属反应
Virus
宿主/亚型
Mouse
/ IgG1
分类
Monoclonal
类型
Antibody
克隆号
0635
抗原
Proprietary sequence
偶联物
形式
Liquid
浓度
100 µg/mL
纯化类型
Protein A
保存液
PBS, pH 7.2
内含物
0.1% sodium azide
保存条件
4° C
运输条件
Wet ice
RRID
AB_2942589
产品详细信息
Specificity: specific for the fusion protein of RSV, types A&B. Non-reactive with: Influenza A & B, Adenovirus, Para 1-3, Measles, Mumps.
Best ELISA pairs (capture/conjugate): RSV Fusion Protein Polyclonal antibody (Product # MA1-7286)/RSV Fusion Protein Monoclonal antibody (Product # MA5-47608); RSV Fusion Protein Monoclonal antibody (Product # MA1-7287)/RSV Fusion Protein Monoclonal antibody (Product # MA5-47608); RSV Fusion Protein Polyclonal antibody (Product # MA1-7081)/RSV Fusion Protein Monoclonal antibody (Product # MA5-47608); RSV Fusion Protein Monoclonal antibody (Product # MA5-47608)/RSV Fusion Protein Monoclonal antibody (Product # MA1-7287).
Purified preparations consist of >90% pure mouse monoclonal antibody which has been purified from ascites fluid by protein A chromatography. The final preparation is formulated to a protein concentration of 100 µg/mL in 0.01 M phosphate buffered saline, pH 7.2 and contains 0.1% sodium azide. Each vial contains 1.0 ml. This product contains no stabilizing proteins and should be stored at 4C until ready for use. Working dilution must be determined by the user. Suggested starting ranges are 1:10-1:50 for ICC/IF and 1:20-1:200. for ELISA.
靶标信息
Human respiratory syncytial virus (RSV) is a member of the Paramyxoviridae family, subfamily Pneumovirinae, that causes common respiratory tract infections such as measles and mumps. Its genome consists of single stranded, negative sense RNA that encodes three envelope glycoproteins, a small hydrophobic (SH) protein of unknown function, a major glycoprotein (G) known as the attachment protein, and a fusion (F) protein. The 63 kD RSV fusion protein of the RSS 2 strain (subtype A) directs fusion of viral and cellular membranes, resulting in viral penetration, and can direct fusion of infected cells with adjoining cells, resulting in the formation of syncytia or multi nucleated giant cells. Its name comes from the fact that F proteins on the surface of the virus cause the membranes on nearby cells to merge, forming syncytia. While RSV typically produces mild symptoms in adults, it is one of the leading causes of lower respiratory tract infections and hospital visits during infancy and childhood.
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生物信息学
蛋白别名: human respiratory syncytial virus; RSV; RSV Fusion protein; Rsvgp08
