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产品信息
PA5-34174
产品规格
种属反应
Horse,
Human,
Mouse
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Synthetic 14 amino acid peptide from 2nd cytoplasmic domain of human RXFP2.
偶联物
Unconjugated
形式
Liquid
浓度
1 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS
内含物
0.1% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
AB_2551527
产品详细信息
Percent identity with other species by BLAST analysis: Human, Gorilla, Gibbon, Marmoset, Horse (100%) Monkey, Panda (93%) Dog, Pig, Xenopus (86%).
靶标信息
The activity of this relaxin receptor is mediated by G proteins leading to stimulation of adenylate cyclase and an increase of cAMP and may also be a receptor for Leydig insulin-like peptide. Expressed in embryonic and adult gonads of males and females, as well in male gubernarculum and in brain. Not detected in kidney, spleen and heart.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: G protein coupled receptor affecting testicular descent; G protein-coupled receptor 106; G-protein coupled receptor 106; G-protein coupled receptor affecting testicular descent; INSL3/relaxin receptor LGR8; leucine-rich repeat-containing G protein-coupled receptor 8; Leucine-rich repeat-containing G-protein coupled receptor 8; Relaxin family peptide receptor 2; Relaxin receptor 2; relaxin/insulin like family peptide receptor 2; relaxin/insulin-like family peptide receptor 2
基因别名: GPR106; GREAT; INSL3R; LGR8; LGR8.1; RXFP2; RXFPR2
UniProt ID: (Human) Q8WXD0, (Mouse) Q91ZZ5
Entrez Gene ID: (Human) 122042, (Horse) 100033993, (Mouse) 140498
oocyte maturation
adenylate cyclase-modulating G-protein coupled receptor signaling pathway
adenylate cyclase-activating G-protein coupled receptor signaling pathway
adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway
negative regulation of cell proliferation
male gonad development
positive regulation of cAMP biosynthetic process
negative regulation of apoptotic process
signal transduction
G-protein coupled receptor signaling pathway
