Search Thermo Fisher Scientific
Immunogen sequence: LWELMTLGQT PYVDIDPFEM AAYLKDGYRI AQPINCPDEL FAVMACCWAL DPEERPKFQQ LVQCLTEFHA ALG
RYK is an atypical member of the family of growth factor receptor protein tyrosine kinases, differing from other members at a number of conserved residues in the activation and nucleotide binding domains. This gene product belongs to a subfamily whose members do not appear to be regulated by phosphorylation in the activation segment. It has been suggested that mediation of biological activity by recruitment of a signaling-competent auxiliary protein may occur through an as yet uncharacterized mechanism. A nine nucleotide insertion in some transcripts results in the SLG variant. It is not established whether this is a product of alternative splicing or a second gene, since evidence for a second gene or pseudogene on chromosome 17 exists.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: ERK3; hydroxyaryl-protein kinase; JTK5A protein tyrosine kinase; Tyrosine-protein kinase RYK
基因别名: D3S3195; JTK5; JTK5A; RYK; RYK1
UniProt ID: (Human) P34925
Entrez Gene ID: (Human) 6259