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S100A7 Antibody (PA5-79947) in ICC/IF
Immunocytochemistry analysis of Psoriasin using anti-Psoriasin antibody (Product # PA5-79947). Psoriasin was detected in a section of A431 cells. Enzyme antigen retrieval was performed using IHC enzyme antigen retrieval reagent for 15 mins. The cells were blocked with 10% goat serum and then incubated with 2μg/mL rabbit anti-Psoriasin antibody (Product # PA5-79947) overnight at 4°C. Cy3 Conjugated Goat Anti-Rabbit IgG was used as secondary antibody at 1:100 dilution and incubated for 30 minutes at 37°C. The section was counterstained with ... View More
产品信息
PA5-79947
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
E. coli-derived human Psoriasin recombinant protein (Position: S2-Q101).
偶联物
形式
Lyophilized
浓度
500 µg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS with 4mg trehalose
内含物
0.05mg sodium azide
保存条件
-20°C
运输条件
Wet ice
RRID
AB_2747062
产品详细信息
Reconstitute with 0.2 mL of distilled water to yield a concentration of 500 µg/mL.
靶标信息
The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. This protein differs from the other S100 proteins of known structure in its lack of calcium binding ability in one EF-hand at the N-terminus. This protein is markedly over-expressed in the skin lesions of psoriatic patients, but is excluded as a candidate gene for familial psoriasis susceptibility. The exact function of this protein is not known.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Protein S100-A15A; Protein S100-A7; Protein S100-A7A; Psoriasin; psoriasin 1; S100 calcium binding protein A15; S100 calcium binding protein A7-like 1; S100 calcium-binding protein A15; S100 calcium-binding protein A15A; S100 calcium-binding protein A7; S100 calcium-binding protein A7 (psoriasin 1); S100 calcium-binding protein A7A
基因别名: AY465109; Gm1020; PSOR1; S100a15; S100a15a; S100a17l1; S100A7; S100a7a; S100A7C; S100A7f; S100A7L1
UniProt ID: (Human) P31151, (Mouse) Q6S5I3
Entrez Gene ID: (Human) 6278, (Mouse) 381493
response to reactive oxygen species
angiogenesis
epidermis development
positive regulation of T cell chemotaxis
keratinocyte differentiation
response to lipopolysaccharide
innate immune response
defense response to Gram-negative bacterium
sequestering of metal ion
positive regulation of ERK1 and ERK2 cascade
positive regulation of granulocyte chemotaxis
positive regulation of monocyte chemotaxis
inflammatory response
cytokine metabolic process
positive chemotaxis
