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May be stored for twelve months without detectable loss of activity. Protect from prolonged exposure to light and do not freeze. Sodium azide is toxic to cells and should be disposed of properly so flush with large volumes of water during disposal.
The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. This protein differs from the other S100 proteins of known structure in its lack of calcium binding ability in one EF-hand at the N-terminus. This protein is markedly over-expressed in the skin lesions of psoriatic patients, but is excluded as a candidate gene for familial psoriasis susceptibility. The exact function of this protein is not known.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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蛋白别名: Protein S100-A7; Psoriasin; psoriasin 1; S100 calcium-binding protein A7; S100 calcium-binding protein A7 (psoriasin 1)
基因别名: PSOR1; S100A7; S100A7C
UniProt ID: (Human) P31151
Entrez Gene ID: (Human) 6278