Search Thermo Fisher Scientific
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
图: 1 / 1
SBF1 Antibody (PA5-88490) in WB
Western blot analysis of SBF1 in extracts of various cell lines. Samples were incubated with SBF1 Polyclonal antibody (Product # PA5-88490) using a dilution of 1:3,000, followed by HRP Goat Anti-Rabbit IgG (H+L) at a dilution of 1:10,000. Lysates/proteins: 25 µg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 90s.
产品信息
PA5-88490
产品规格
种属反应
Human,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant fusion protein containing a sequence corresponding to amino acids 1630-1770 of human SBF1 (NP_0029632)
偶联物
形式
Liquid
浓度
1.73 mg/mL
纯化类型
Affinity Chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.01% thimerosal
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Wet ice
RRID
AB_2804949
产品详细信息
Immunogen sequence: PPYDWELAQG PPEPPEEERS DGGAPQSRRR VVWPCYDSCP RAQPDAISRL LEELQRLETE LGQPAERWKD TWDRVKAAQR LEGRPDGRGT PSSLLVSTAP HHRRSLGVYL QEGPVGSTLS LSLDSDQSSG STTSGSRQAA R; Positive Samples: Raji, Jurkat, Rat brain; Cellular Location: Nucleus
靶标信息
Probable pseudophosphatase. Lacks several amino acids in the catalytic pocket which renders it catalytically inactive as a phosphatase. The pocket is however sufficiently preserved to bind phosphorylated substrates, and maybe protect them from phosphatases. Inhibits myoblast differentiation in vitro and induces oncogenic transformation in fibroblasts. According to PubMed:20937701, may function as a guanine nucleotide exchange factor (GEF) activating RAB28. Promotes the exchange of GDP to GTP, converting inactive GDP-bound Rab proteins into their active GTP-bound form.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
篇参考文献 (0)
您是否在文献中引用过该产品？请点击下方按钮邮件告知我们。
生物信息学
蛋白别名: DENN/MADD domain containing 7A; Inactive phosphatidylinositol 3-phosphatase 5; Myotubularin-related protein 5; Sbf1; SET-binding factor 1
基因别名: CMT4B3; DENND7A; MTMR5; SBF1
UniProt ID: (Human) O95248
Entrez Gene ID: (Human) 6305, (Rat) 300147
