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SCFD1 Antibody (MA5-25948) in IHC (P)
Immunohistochemistry was performed on paraffin-embedded adenocarcinoma of human endometrium tissue. To expose target proteins, 10mM citric buffer, pH6.0, 100°C for 10min was used. Following antigen retrieval, tissues were probed with a SCFD1 monoclonal antibody (Product # MA5-25948).
产品信息
MA5-25948
产品规格
种属反应
Dog,
Human,
Rat
宿主/亚型
Mouse
/ IgG1
分类
Monoclonal
类型
Antibody
克隆号
OTI2E7
抗原
Full length human recombinant protein of SCFD1 produced in HEK293T cell
偶联物
形式
Liquid
浓度
0.87 mg/mL
纯化类型
Affinity Chromatography
保存液
PBS, pH 7.3, with 1% BSA, 50% glycerol
内含物
0.02% sodium azide
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
RRID
AB_2723612
靶标信息
The de novo synthesis of pyrimidine nucleotides is required for mammalian cells to proliferate. This gene encodes a trifunctional protein which is associated with the enzymatic activities of the first 3 enzymes in the 6-step pathway of pyrimidine biosynthesis: carbamoylphosphate synthetase (CPS II), aspartate transcarbamoylase, and dihydroorotase. This protein is regulated by the mitogen-activated protein kinase (MAPK) cascade, which indicates a direct link between activation of the MAPK cascade and de novo biosynthesis of pyrimidine nucleotides.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Sec1 family domain-containing protein 1; SLY1 homolog; Sly1p; Syntaxin-binding protein 1-like 2; vesicle transport-related protein; Vesicle transport-related protein Ra410
基因别名: C14orf163; FKSG23; KIAA0917; RA410; rSly1; SCFD1; SLY1; SLY1P; STXBP1L2
UniProt ID: (Human) Q8WVM8, (Rat) Q62991
Entrez Gene ID: (Dog) 480281, (Human) 23256, (Rat) 54350
cell morphogenesis
response to hypoxia
retrograde vesicle-mediated transport, Golgi to ER
post-Golgi vesicle-mediated transport
vesicle docking involved in exocytosis
phagocytosis
response to toxic substance
protein transport
COPII vesicle coating
regulation of protein transport
regulation of ER to Golgi vesicle-mediated transport
toxin transport
negative regulation of autophagosome assembly
ER to Golgi vesicle-mediated transport
