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产品信息
642658-MSM2-P1
应用
建议稀释比
已发表文章
产品规格
种属反应
Human
宿主/亚型
Mouse
/ IgG2a
分类
Monoclonal
类型
Antibody
克隆号
PCRP-SCXA-2D11
抗原
Recombinant full-length human SCXA protein
偶联物
形式
Liquid
浓度
200 µg/mL
纯化类型
Protein A/G
保存液
PBS, pH 7.4, with 0.05% BSA
内含物
0.05% sodium azide
保存条件
4° C
运输条件
Ambient (domestic); Wet ice (international)
靶标信息
Enables DNA-binding transcription activator activity, RNA polymerase II-specific and bHLH transcription factor binding activity. Contributes to E-box binding activity. Involved in positive regulation of transcription by RNA polymerase II. Located in nucleus. Part of transcription regulator complex.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Basic helix-loop-helix transcription factor scleraxis; bHLHa41; bHLHa48; Class A basic helix-loop-helix protein 41; Class A basic helix-loop-helix protein 48; class II bHLH protein scleraxis; scleraxis basic helix-loop-helix transcription factor; scleraxis homolog A; scleraxis homolog B
基因别名: BHLHA41; BHLHA48; SCX; SCXA; SCXB
UniProt ID: (Human) Q7RTU7
Entrez Gene ID: (Human) 642658
RNA polymerase II distal enhancer sequence-specific DNA binding
transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding
DNA binding
bHLH transcription factor binding
sequence-specific DNA binding
protein heterodimerization activity
E-box binding
basic helix-loop-helix transcription factor
mesoderm formation
tissue homeostasis
endochondral ossification
chondrocyte differentiation
heart valve morphogenesis
heart valve formation
transcription, DNA-templated
transcription from RNA polymerase II promoter
positive regulation of cell proliferation
positive regulation of gene expression
cell differentiation
collagen fibril organization
BMP signaling pathway
positive regulation of collagen biosynthetic process
skeletal muscle cell differentiation
tendon development
tendon cell differentiation
tendon formation
deltoid tuberosity development
negative regulation of apoptotic process
negative regulation of transcription, DNA-templated
positive regulation of transcription, DNA-templated
positive regulation of transcription from RNA polymerase II promoter
embryonic skeletal system development
Sertoli cell differentiation
face morphogenesis
regulation of cartilage development
positive regulation of cartilage development
sclerotome development
cellular response to mechanical stimulus
cellular response to transforming growth factor beta stimulus
positive regulation of gastrulation
