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产品信息
H00006385-D01P
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
SDC4 (NP_002990.2, 1 a.a. approximately 198 a.a) full-length human protein.
偶联物
Unconjugated
形式
Liquid
浓度
0.5-1 mg/mL
纯化类型
Protein A
保存液
PBS, pH 7.4
内含物
no preservative
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
产品详细信息
Product may be used with Western Blot (Transfected lysate).
The Isotype of this product is composed of an IgG Mixture.
Immunogen sequence: MAPARLFALL LFFVGGVAES IRETEVIDPQ DLLEGRYFSG ALPDDEDVVG PGQESDDFEL SGSGDLDDLE DSMIGPEVVH PLVPLDNHIP ERAGSGSQVP TEPKKLEENE VIPKRISPVE ESEDVSNKVS MSSTVQGSNI FERTEVLAAL IVGGIVGILF AVFLILLLMY RMKKKDEGSY DLGKKPIYKK APTNEFYA
靶标信息
Syndecans are type I integral membrane proteoglycans that are involved in cell-extracellular matrix adhesion and growth factor binding. Syndecan 1 is a matrix receptor which binds to Collagens, Fibronectin and Thrombospondin. Syndecan 1 and Syndecan 3 interact with MK (midkine), a growth/differentiation factor involved in embryogenesis. Syndecan 2 is highly expressed at areas of high morphogenetic activity, such as epithelial-mesenchymal interfaces and the prechondrogenic and preosteogenic mesenchymal condensations. Syndecan 4 functions cooperatively with integrins in the processes of cell spreading and focal adhesion assembly.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Amphiglycan; MGC22217; ryudocan amphiglycan; Ryudocan core protein; SYND4; syndecan 4 (amphiglycan, ryudocan); syndecan proteoglycan 4; Syndecan-4
基因别名: SDC4; SYND4
UniProt ID: (Human) P31431
Entrez Gene ID: (Human) 6385
retinoid metabolic process
ureteric bud development
neural tube closure
glycosaminoglycan biosynthetic process
glycosaminoglycan catabolic process
signal transduction
regulation of fibroblast migration
cell migration
glycosaminoglycan metabolic process
wound healing
positive regulation of protein kinase activity
positive regulation of stress fiber assembly
positive regulation of focal adhesion assembly
inner ear receptor stereocilium organization
positive regulation of exosomal secretion
positive regulation of extracellular exosome assembly
