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SEMA3F Antibody (PA5-57111) in IHC (P)
Immunohistochemical analysis of SEMA3F in human pancreas using SEMA3F Polyclonal Antibody (Product # PA5-57111) shows strong membranous and cytoplasmic positivity in islets of Langerhans.
产品信息
PA5-57111
产品规格
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
偶联物
Unconjugated
形式
Liquid
浓度
0.1 mg/mL
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
AB_2647107
产品详细信息
Immunogen sequence: TPPYQELAQL LAQPEVGLIH QYCQGYWRHV PPSPREAPGA PRSPEPQDQK KPRNRRHHPP DT
Highest antigen sequence identity to the following orthologs: Mouse - 94%, Rat - 94%.
靶标信息
The semaphorins are a family of proteins that are involved in signaling. All the family members have a secretion signal, a 500-amino acid sema domain, and 16 conserved cysteine residues (Kolodkin et al., 1993 [PubMed 8269517]). Sequence comparisons have grouped the secreted semaphorins into 3 general classes, all of which also have an immunoglobulin domain. The semaphorin III family, consisting of human semaphorin III (SEMA3A; MIM 603961), chicken collapsin, and mouse semaphorins A, D, and E, all have a basic domain at the C terminus. Chicken collapsin contributes to path finding by axons during development by inhibiting extension of growth cones (Luo et al., 1993 [PubMed 8402908]) through an interaction with a collapsin response mediator protein of relative molecular mass 62K (CRMP62) (Goshima et al., 1995 [PubMed 7637782]), a putative homolog of an axonal guidance associated UNC33 gene product (MIM 601168). SEMA3F is a secreted member of the semaphorin III family.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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