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产品信息
PA5-30884
应用
建议稀释比
已发表文章
产品规格
种属反应
Human
已发表种属
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant fragment corresponding to a region within amino acids 13 and 245 of Human Semaphorin 5A
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7, with 1% BSA, 20% glycerol
内含物
0.01% thimerosal
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Wet ice
RRID
AB_2548358
产品详细信息
Recommended positive controls: U87-MG.
Predicted reactivity: Mouse (97%), Rat (97%), Zebrafish (83%), Rhesus Monkey (100%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
靶标信息
Members of the semaphorin protein family, such as SEMA5A, are involved in axonal guidance during neural development (Adams et al., 1996 [PubMed 8817451]).
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A; Sema F; semaphorin F; Semaphorin-5A; Semaphorin-F
基因别名: SEMA5A; SEMAF; semF
UniProt ID: (Human) Q13591
Entrez Gene ID: (Human) 9037
neural crest cell migration
positive regulation of endothelial cell proliferation
blood vessel endothelial cell proliferation involved in sprouting angiogenesis
cell adhesion
negative regulation of cell adhesion
cell-cell signaling
nervous system development
axonal fasciculation
diencephalon development
positive regulation of cell migration
positive regulation of actin filament depolymerization
positive regulation of catenin import into nucleus
positive regulation of angiogenesis
positive regulation of axon extension involved in axon guidance
negative regulation of axon extension involved in axon guidance
positive chemotaxis
negative chemotaxis
positive regulation of protein kinase B signaling
cell chemotaxis
semaphorin-plexin signaling pathway
signal clustering
negative regulation of endothelial cell apoptotic process
positive regulation of endothelial cell chemotaxis
