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Septin 1 (SEPT1) is a member of the septin family of GTPases. Members of this family are required for cytokinesis and the maintenance of cellular morphology. This gene encodes a protein that can form homo- and heterooligomeric filaments, and may contribute to the formation of neurofibrillary tangles in Alzheimer's disease. Alternatively spliced transcript variants have been found but the full-length nature of these variants has not been determined.
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Protein Aliases: 1-Sep; differentiation 6; differentiation 6 (deoxyguanosine triphosphate triphosphohydrolase); Differentiation protein 6; LARP; MGC20394; Peanut-like protein 3; Protein Diff6; Septin-1; Serologically defined breast cancer antigen NY-BR-24
Gene Aliases: DIFF6; LARP; PNUTL3; SEP1; SEPT1; SEPTIN1
UniProt ID: (Human) Q8WYJ6, (Mouse) P42209, (Rat) Q5EB96
Entrez Gene ID: (Human) 1731, (Mouse) 54204, (Rat) 293507
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