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SERPINB6 Antibody (MA5-25823) in IHC (P)
Immunohistochemistry was performed on paraffin-embedded adenocarcinoma of human endometrium tissue. To expose target proteins, 10mM citric buffer, pH6.0, 100°C for 10min was used. Following antigen retrieval, tissues were probed with a SERPINB6 monoclonal antibody (Product # MA5-25823).
产品信息
MA5-25823
产品规格
种属反应
Human,
Mouse,
Non-human primate
宿主/亚型
Mouse
/ IgG2a
分类
Monoclonal
类型
Antibody
克隆号
OTI1C5
抗原
Full length human recombinant protein of SERPINB6 produced in HEK293T cell
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Affinity Chromatography
保存液
PBS, pH 7.3, with 1% BSA, 50% glycerol
内含物
0.02% sodium azide
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
RRID
AB_2723637
靶标信息
The protein encoded by this gene is a member of the serpin superfamily, and ovalbumin-serpin subfamily. It was originally discovered as a placental thrombin inhibitor. The mouse homolog was found to be expressed in the hair cells of the inner ear. Mutations in this gene are associated with nonsyndromic progressive hearing loss, suggesting that this serpin plays an important role in the inner ear in the protection against leakage of lysosomal content during stress, and that loss of this protection results in cell death and sensorineural hearing loss. Alternatively spliced transcript variants have been found for this gene.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: CAP; Cytoplasmic antiproteinase; DKFZp686I04222; MGC111370; Peptidase inhibitor 6; PI-6; Placental thrombin inhibitor; protease inhibitor 6 (placental thrombin inhibitor); Proteinase inhibitor 6; RP1-90J20.6; serine (or cysteine) proteinase inhibitor, clade B (ovalbumin), member 6; serine (or cysteine) proteinase inhibitor, clade B, member 6a; serine protease inhibitor 3; Serpin B6; serpin peptidase inhibitor, clade B (ovalbumin), member 6
基因别名: 4930482L21Rik; CAP; D330015H01Rik; DFNB91; MSTP057; ovalbumin; PI-6; PI6; PTI; SERPINB6; Serpinb6a; SPI3
UniProt ID: (Human) P35237, (Mouse) Q60854
Entrez Gene ID: (Human) 5269, (Mouse) 20719
