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Invitrogen

SESN2 Polyclonal Antibody

6个已发表图片

5 篇参考文献

查看其他17个SESN2抗体

说明书

实验方案

技术支持

货号 PA5-72834

CNY 5,129.00

100 µg

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说明书

实验方案

技术支持

抗体检测数据 (3)
已发表图片 (6)

Application

SESN2 Antibody in Immunohistochemistry (Paraffin) (IHC (P))

图: 1 / 9

SESN2 Antibody (PA5-72834) in IHC (P)

Immunohistochemistry of SESTRIN2 in mouse kidney tissue with SESN2 Polyclonal Antibody (Product # PA5-72834) at 5 µg/mL.

SESN2 Antibody in Western Blot, Immunocytochemistry (WB, ICC/IF)

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产品信息

PA5-72834

应用

建议稀释比

已发表文章

免疫印迹 (WB)

1-2 µg/mL

查看3篇已发表文章 3篇已发表文章

免疫组化（石蜡） (IHC (P))

5 µg/mL

查看1篇已发表文章 1篇已发表文章

免疫细胞化学 (ICC/IF)

查看1篇已发表文章 1篇已发表文章

酶联免疫吸附实验 (ELISA)

Assay-Dependent

产品规格

种属反应

Human, Mouse, Rat

已发表种属

Mouse

宿主/亚型

Rabbit / IgG

分类

Polyclonal

类型

Antibody

抗原

SESTRIN2 antibody for a 19 amino acid peptide near the center of human SESTRIN2. The immunogen is within amino acids 220 - 270 of SESTRIN2.

查看免疫原

偶联物

Unconjugated

形式

Liquid

浓度

1 mg/mL

纯化类型

Antigen affinity chromatography

保存液

PBS

内含物

0.02% sodium azide

保存条件

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

运输条件

Ambient (domestic); Wet ice (international)

RRID

AB_2718688

靶标信息

This gene encodes a member of the sestrin family of PA26-related proteins. The encoded protein may function in the regulation of cell growth and survival. This protein may be involved in cellular response to different stress conditions.

仅用于科研。不用于诊断过程。未经明确授权不得转售。

Product References

MicroRNA-34a-5p promotes the progression of osteoarthritis secondary to developmental dysplasia of the hip by restraining SESN2-induced autophagy.

Journal of orthopaedic research : official publication of the Orthopaedic Research Society

Wang J,Li X,Guo X,Wang C,Liu Z,Liu X,Sun Y,Chen X,Zhang Y,Chen G

Published figure using SESN2 polyclonal antibody (Product # PA5-72834) in Western Blot

Mon Jan 01 00:00:00 UTC 2024

Sestrin Proteins Protect Against Lipotoxicity-Induced Oxidative Stress in the Liver via Suppression of C-Jun N-Terminal Kinases.

Cellular and molecular gastroenterology and hepatology

Fang Z,Kim HG,Huang M,Chowdhury K,Li MO,Liangpunsakul S,Dong XC

Published figure using SESN2 polyclonal antibody (Product # PA5-72834) in Western Blot

Tue Mar 22 00:00:00 UTC 2022

Sestrin 2 attenuates sepsis-associated encephalopathy through the promotion of autophagy in hippocampal neurons.

Journal of cellular and molecular medicine

Luo L,Wu J,Qiao L,Lu G,Li J,Li D

PA5-72834 was used in Western Blot, Immunohistochemistry (Paraffin) to demonstrate that SESN2 might be a novel pharmacological intervention strategy for SAE treatment through promotion of ULK1-dependent autophagy in hippocampal neurons.

Mon Jun 01 00:00:00 UTC 2020

Sestrin 2 attenuates sepsis-associated encephalopathy through the promotion of autophagy in hippocampal neurons.

Journal of cellular and molecular medicine

Luo L,Wu J,Qiao L,Lu G,Li J,Li D

Mon Jun 01 00:00:00 UTC 2020

Sestrin 2 attenuates sepsis-associated encephalopathy through the promotion of autophagy in hippocampal neurons.

Journal of cellular and molecular medicine

Luo L,Wu J,Qiao L,Lu G,Li J,Li D

Mon Jun 01 00:00:00 UTC 2020

Sestrin 2 attenuates sepsis-associated encephalopathy through the promotion of autophagy in hippocampal neurons.

Journal of cellular and molecular medicine

Luo L,Wu J,Qiao L,Lu G,Li J,Li D

Mon Jun 01 00:00:00 UTC 2020

生物信息学

蛋白别名: hypoxia induced gene 95; hypoxia-induced; Hypoxia-induced gene; Sestrin-2

基因别名: HI95; RGD1566319; SES2; SESN2; SEST2

UniProt ID: (Human) P58004, (Mouse) P58043

Entrez Gene ID: (Human) 83667, (Rat) 502988, (Mouse) 230784

功能

protein binding oxidoreductase activity, acting on peroxide as acceptor sulfiredoxin activity leucine binding peroxidase

参与通路

regulation of protein phosphorylation fatty acid beta-oxidation autophagy response to glucose positive regulation of macroautophagy negative regulation of cell growth DNA damage response, signal transduction by p53 class mediator mitochondrial DNA metabolic process response to insulin cellular response to oxidative stress positive regulation of transcription from RNA polymerase II promoter in response to oxidative stress protein kinase B signaling glucose import triglyceride homeostasis cellular response to amino acid stimulus cellular response to leucine reactive oxygen species metabolic process regulation of gluconeogenesis involved in cellular glucose homeostasis cellular oxidant detoxification positive regulation of protein localization to nucleus regulation of response to reactive oxygen species negative regulation of translation in response to endoplasmic reticulum stress negative regulation of TORC1 signaling regulation of cAMP-dependent protein kinase activity mitochondrion organization glucose homeostasis

SESN2 Polyclonal Antibody

SESN2 Antibody (PA5-72834) in IHC (P)

产品信息

PA5-72834

免疫印迹 (WB)

免疫组化（石蜡） (IHC (P))

免疫细胞化学 (ICC/IF)

酶联免疫吸附实验 (ELISA)

种属反应

已发表种属

宿主/亚型

分类

类型

抗原

偶联物

形式

浓度

纯化类型

保存液

内含物

保存条件

运输条件

RRID

靶标信息

生物信息学

性能保障

随时为您服务

Your items have has been added!

SESN2 Polyclonal Antibody

SESN2 Antibody (PA5-72834) in IHC (P)

产品信息

PA5-72834

免疫印迹 (WB)

免疫组化（石蜡） (IHC (P))

免疫细胞化学 (ICC/IF)

酶联免疫吸附实验 (ELISA)

种属反应

已发表种属

宿主/亚型

分类

类型

抗原

偶联物

形式

浓度

纯化类型

保存液

内含物

保存条件

运输条件

RRID .st0{fill-rule:evenodd;clip-rule:evenodd;fill:#A2A2A2;}

靶标信息

生物信息学

性能保障

随时为您服务

Your items have has been added!

RRID