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产品信息
MA5-15722
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse,
Non-human primate
已发表种属
Mouse
宿主/亚型
Mouse
/ IgG1
分类
Monoclonal
类型
Antibody
克隆号
5H6A12
抗原
Purified recombinant fragment of human SETDB1 expressed in E. Coli.
偶联物
形式
Liquid
浓度
Conc. not determined
保存液
ascites
内含物
0.03% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Wet ice
RRID
AB_10988015
产品详细信息
MA5-15722 targets SETDB1 in indirect ELISA, IF and WB applications and shows reactivity with Human, mouse, and Non-human primate samples.
The MA5-15722 immunogen is purified recombinant fragment of human SETDB1 expressed in E. Coli.
MA5-15722 detects SETDB1 which has a predicted molecular weight of approximately 180kDa.
靶标信息
This gene encodes a histone methyltransferase. The encoded enzyme catalyzes the reaction of S-adenosyl-L-methionine and histone L-lysine to produce S-adenosyl-L-homocysteine and histone N(6)-methyl-L-lysine. The encoded protein likely functions in transcriptional repression. Alternatively spliced transcript variants have been described.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: ERG-associated protein with a SET domain, ESET; ERG-associated protein with SET domain; ESET; H3-K9-HMTase 4; Histone H3-K9 methyltransferase 4; Histone-lysine N-methyltransferase SETDB1; histone-lysine N-methyltransferase, H3lysine-9 specific 4; Lysine N-methyltransferase 1E; SET domain bifurcated 1; SET domain ERG-associated histone methyltransferase; SET domain, bifurcated 1; tudor domain containing 21
基因别名: AU022152; ESET; H3-K9-HMTase4; KG1T; KIAA0067; KMT1E; mKIAA0067; SETDB1; TDRD21
UniProt ID: (Human) Q15047
Entrez Gene ID: (Human) 9869, (Mouse) 84505
transcription, DNA-templated
Ras protein signal transduction
response to vitamin
histone lysine methylation
response to ethanol
positive regulation of methylation-dependent chromatin silencing
negative regulation of transcription from RNA polymerase II promoter
inner cell mass cell proliferation
regulation of transcription, DNA-templated
chromatin modification
methylation
histone H3-K9 trimethylation
bone development
