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Antibody detects endogenous levels of total SF3B3.
This gene encodes subunit 3 of the splicing factor 3b protein complex. Splicing factor 3b, together with splicing factor 3a and a 12S RNA unit, forms the U2 small nuclear ribonucleoproteins complex transcription coactivator-HAT complex, and the TFTC -containing complex). These complexes may function in chromatin modification, transcription, splicing, and DNA repair.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: pre-mRNA splicing factor SF3b, 130 kDa subunit; Pre-mRNA-splicing factor SF3b 130 kDa subunit; SAP 130; SF3b130; Spliceosome-associated protein 130; Splicing factor 3B subunit 3; STAF130
基因别名: 1810061H24Rik; 5730409A01Rik; AA409318; D8Ertd633e; KIAA0017; mKIAA0017; RSE1; SAP130; SF3b130; SF3B3; STAF130
UniProt ID: (Human) Q15393, (Mouse) Q921M3
Entrez Gene ID: (Human) 23450, (Mouse) 101943
分子生物学功能:
RNA processing factor