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产品信息
SGK3-301Y
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Chicken
/ IgY
分类
Polyclonal
类型
Antibody
抗原
Synthetic peptide taken within amino acid region 440-490 on human Sgk3 protein.
偶联物
Unconjugated
形式
Liquid
浓度
0.5-1.5 mg/mL
纯化类型
Affinity chromatography
保存液
proprietary buffer, pH 7.4-7.8, with 30% glycerol, 0.5% BSA
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Ambient (domestic); Wet ice (international)
靶标信息
SGKL (SGK3) is a serine/threonine protein kinase which is similar to serum- and glucocorticoid-induced protein kinase (SGK). Unlike SGK, SGKL is not induced by serum or glucocorticoids. It is induced in response to signals that activate phosphatidylinositol 3-kinase, which is also true for SGK. The protein phosphorylates several target proteins and has a role in neutral amino acid transport and activation of potassium and chloride channels. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Cytokine-independent survival kinase; DKFZp781N0293; Serine/threonine-protein kinase Sgk3; serum/glucocorticoid regulated kinase 3; Serum/glucocorticoid-regulated kinase 3; Serum/glucocorticoid-regulated kinase-like
基因别名: 2510015P22Rik; A330005P07Rik; CISK; fy; fz; SGK2; SGK3; SGKL
UniProt ID: (Human) Q96BR1, (Mouse) Q9ERE3
Entrez Gene ID: (Human) 23678, (Mouse) 170755, (Rat) 171498
protein kinase activity
protein serine/threonine kinase activity
calcium channel regulator activity
protein binding
ATP binding
potassium channel regulator activity
sodium channel regulator activity
chloride channel regulator activity
phosphatidylinositol binding
nucleotide binding
kinase activity
transferase activity
transferase activity, transferring phosphorus-containing groups
non-receptor serine/threonine protein kinase
regulation of cell growth
protein phosphorylation
cellular sodium ion homeostasis
response to stress
positive regulation of sodium ion transport
peptidyl-serine phosphorylation
regulation of cell migration
positive regulation of transporter activity
ion transmembrane transport
intracellular signal transduction
regulation of cell proliferation
regulation of apoptotic process
regulation of sequence-specific DNA binding transcription factor activity
phosphorylation
negative regulation of extrinsic apoptotic signaling pathway in absence of ligand
