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产品信息
PA1-12492
产品规格
种属反应
Mouse
宿主/亚型
Sheep
/ IgG
分类
Polyclonal
类型
Antibody
抗原
SH2 domain of the 3BP2 protein fused to GST.
偶联物
形式
Liquid
浓度
1.0 mg/mL
纯化类型
Ammonium sulfate precipitation
保存液
PBS
内含物
0.08% sodium azide
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
RRID
AB_2254750
产品详细信息
A suggested positive control for this product is recombinant 3BP2 protein.
靶标信息
The protein encoded by this gene has an N-terminal pleckstrin homology (PH) domain, an SH3-binding proline-rich region, and a C-terminal SH2 domain. The protein binds to the SH3 domains of several proteins including the ABL1 and SYK protein tyrosine kinases, and functions as a cytoplasmic adaptor protein to positively regulate transcriptional activity in T, natural killer (NK), and basophilic cells. Mutations in this gene result in cherubism. Multiple transcript variants encoding different isoforms have been found for this gene.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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