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SIX2 Monoclonal Antibody (1G11)

查看其他7个SIX2抗体

产品信息

H00010736-M02

应用

建议稀释比

已发表文章

免疫印迹 (WB)

1-5 µg/mL

-

酶联免疫吸附实验 (ELISA)

10 µg/mL

-

产品规格

种属反应

Human

宿主/亚型

Mouse / IgG1, kappa

分类

Monoclonal

类型

Antibody

克隆号

1G11

抗原

SIX2 (AAH24033, 1 a.a. approximately 291 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

0.5 mg/mL

纯化类型

Protein A

保存液

PBS, pH 7.4

内含物

no preservative

保存条件

-20° C, Avoid Freeze/Thaw Cycles

运输条件

Ambient (domestic); Wet ice (international)

产品详细信息

Immunogen sequence: MSMLPTFGFT QEQVACVCEV LQQGGNIERL GRFLWSLPAC EHLHKNESVL KAKAVVAFHR GNFRELYKIL ESHQFSPHNH AKLQQLWLKA HYIEAEKLRG RPLGAVGKYR VRRKFPLPRS IWDGEETSYC FKEKSRSVLR EWYAHNPYPS PREKRELTEA TGLTTTQVSN WFKNRRQRDR AAEAKERENN ENSNSNSHNP LNGSGKSVLG SSEDEKTPSG TPDHSSSSPA LLLSPPPPGL PSLHSLGHPP GPSAVPVPVP GGGGADPLQH HHGLQDSILN PMSANLVDLG S

靶标信息

This gene is a member of the vertebrate gene family which encode proteins homologous to the Drosophila 'sine oculis' homeobox protein. SIX2 is a transcription factor which, like other members of this gene family, may be involved in limb or eye development.

仅用于科研。不用于诊断过程。未经明确授权不得转售。

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引用该产品

生物信息学

蛋白别名: Homeobox protein SIX2; Sine oculis homeobox homolog 2

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基因别名: SIX2

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UniProt ID: (Human) Q9NPC8

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Entrez Gene ID: (Human) 10736

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RNA polymerase II core promoter proximal region sequence-specific DNA binding transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding transcription factor activity, sequence-specific DNA binding transcription factor binding protein complex binding homeodomain transcription factor

参与通路

kidney development chondrocyte differentiation mesenchymal to epithelial transition involved in metanephros morphogenesis transcription from RNA polymerase II promoter protein import into nucleus mesodermal cell fate specification cell proliferation anatomical structure morphogenesis anterior/posterior axis specification cell migration regulation of ossification regulation of chondrocyte differentiation middle ear morphogenesis negative regulation of cell differentiation positive regulation of transcription from RNA polymerase II promoter embryonic digestive tract morphogenesis embryonic cranial skeleton morphogenesis nephron development nephron morphogenesis mesenchymal stem cell maintenance involved in nephron morphogenesis mesenchymal cell differentiation involved in kidney development regulation of branching involved in ureteric bud morphogenesis mesenchymal stem cell proliferation positive regulation of chondrocyte proliferation