Invitrogen

SKIP Polyclonal Antibody

查看其他6个SKIP抗体

抗体检测数据 (2)

SKIP Antibody in Immunohistochemistry (Paraffin) (IHC (P))

SKIP Antibody in Immunohistochemistry (Paraffin) (IHC (P))

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SKIP Antibody (PA5-98866) in IHC (P)

Immunohistochemical analysis of SKIP in paraffin embedded human kidney tissue using a SKIP polyclonal antibody (Product # PA5-98866) at a dilution of 1:100.

SKIP Antibody in Immunohistochemistry (Paraffin) (IHC (P))

SKIP Antibody in Western Blot (WB)

Product Image Gallery

SKIP Antibody in Immunohistochemistry (Paraffin) (IHC (P)) — Immunohistochemical analysis of SKIP in paraffin embedded human kidney tissue using a SKIP polyclonal antibody (Product # PA5-98866) at a dilution of 1:100.

SKIP Antibody in Western Blot (WB) — Western Blot analysis of SKIP using a SKIP Polyclonal antibody (Product # PA5-98866) at a concentration of 4.43 µg/mL. Lane 1: Mouse heart tissue. Lane 2: Mouse brain tissue. Lane 3: Mouse skeletal muscle tissue. Lane 4: Hela whole cell lysate. Lane 5: A549 whole cell lysate. A secondary Goat polyclonal antibody to rabbit IgG was applied at a 1:10,000 dilution. Observed band size: 52 kDa.

产品信息

PA5-98866

应用

建议稀释比

已发表文章

免疫印迹 (WB)

1:1,000-1:5,000

-

免疫组化（石蜡） (IHC (P))

1:20-1:200

-

酶联免疫吸附实验 (ELISA)

Assay-Dependent

-

产品规格

种属反应

Human, Mouse

宿主/亚型

Rabbit / IgG

分类

Polyclonal

类型

Antibody

抗原

Recombinant Human Inositol polyphosphate 5-phosphatase K protein (149-448AA)

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偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

0.86 mg/mL

纯化类型

Antigen affinity chromatography

保存液

PBS, pH 7.3, with 50% glycerol

内含物

0.02% sodium azide

保存条件

-20°C or -80°C if preferred

运输条件

Wet ice

RRID

AB_2813479

靶标信息

This gene encodes a protein with 5-phosphatase activity toward polyphosphate inositol. The protein localizes to the cytosol in regions lacking actin stress fibers. It is thought that this protein may negatively regulate the actin cytoskeleton. Alternatively spliced transcript variants encoding different isoforms have been identified.

仅用于科研。不用于诊断过程。未经明确授权不得转售。

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引用该产品

生物信息学

蛋白别名: Inositol polyphosphate 5-phosphatase K; Phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase; Phosphatidylinositol-4,5-bisphosphate 5-phosphatase; PI-5-phosphatase related; putative PI-5-phosphatase; skeletal muscle and kidney enriched inositol polyphosphate phosphatase; Skeletal muscle and kidney-enriched inositol phosphatase

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基因别名: C62; INPP5K; PPS; SKIP

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UniProt ID: (Human) Q9BT40, (Mouse) Q8C5L6

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Entrez Gene ID: (Human) 51763, (Mouse) 19062

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phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity inositol-polyphosphate 5-phosphatase activity vasopressin receptor activity protein binding inositol bisphosphate phosphatase activity phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase activity phosphatidylinositol trisphosphate phosphatase activity phosphatidylinositol phosphate 5-phosphatase activity lipid phosphatase activity inositol trisphosphate phosphatase activity inositol-1,4,5-trisphosphate 5-phosphatase activity inositol-1,3,4,5-tetrakisphosphate 5-phosphatase activity hydrolase activity phosphatase

参与通路

in utero embryonic development negative regulation of protein phosphorylation regulation of glycogen biosynthetic process negative regulation of protein kinase activity phosphatidylinositol biosynthetic process G-protein coupled receptor signaling pathway negative regulation of peptidyl-threonine phosphorylation negative regulation of glucose transport dephosphorylation actin cytoskeleton organization cellular response to insulin stimulus cellular response to hormone stimulus negative regulation of peptidyl-serine phosphorylation negative regulation of dephosphorylation positive regulation of urine volume glucose homeostasis negative regulation of MAP kinase activity negative regulation by host of viral transcription negative regulation of glycogen biosynthetic process negative regulation of single stranded viral RNA replication via double stranded DNA intermediate negative regulation of transcription, DNA-templated positive regulation of transcription, DNA-templated negative regulation of insulin receptor signaling pathway inositol phosphate dephosphorylation phosphatidylinositol dephosphorylation negative regulation of stress fiber assembly negative regulation of protein kinase B signaling negative regulation of calcium ion transport cellular response to cAMP cellular response to tumor necrosis factor cellular response to epidermal growth factor stimulus protein targeting to plasma membrane negative regulation of protein targeting to membrane ruffle assembly negative regulation of glycogen (starch) synthase activity positive regulation of renal water transport response to insulin