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The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
SLC22A12 is required for efficient urate re-absorption in the kidney. SLC22A12 regulates blood urate levels. SLC22A12 mediates saturable urate uptake by facilitating the exchange of urate against organic anions.The protein encoded by this gene is a urate transporter and urate-anion exchanger which regulates the level of urate in the blood. This protein is an integral membrane protein primarily found in kidney. Two transcript variants encoding different isoforms have been found for this gene.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Organic anion transporter 4-like protein; Renal-specific transporter; RST; solute carrier family 22 (organic anion/cation transporter), member 12; solute carrier family 22 (organic anion/urate transporter), member 12; solute carrier family 22 (organic cation transporter)-like 2; Solute carrier family 22 member 12; URAT1; Urate anion exchanger 1; urate transporter 1; Urate:anion antiporter SLC22A12
基因别名: AI987855; OAT4L; OATL4; RST; SLC22A12; Slc22al2; UNQ6453/PRO34004; URAT1
UniProt ID: (Human) Q96S37, (Rat) Q3ZAV1, (Mouse) Q8CFZ5
Entrez Gene ID: (Human) 116085, (Rat) 365398, (Mouse) 20521