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产品信息
PA5-103662
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
A synthesized peptide derived from human SLC25A14(Accession O95258), corresponding to amino acid residues G246-Y296.
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Affinity chromatography
保存液
PBS, pH 7.4, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Wet ice
RRID
AB_2852996
产品详细信息
Antibody detects endogenous levels of total SLC25A14.
靶标信息
Mitochondrial uncoupling proteins (UCP) are members of the larger family of mitochondrial anion carrier proteins (MACP). UCPs separate oxidative phosphorylation from ATP synthesis with energy dissipated as heat, also referred to as the mitochondrial proton leak. UCPs facilitate the transfer of anions from the inner to the outer mitochondrial membrane and the return transfer of protons from the outer to the inner mitochondrial membrane. They also reduce the mitochondrial membrane potential in mammalian cells. Tissue specificity occurs for the different UCPs and the exact methods of how UCPs transfer H+/OH- are not known. UCPs contain the three homologous protein domains of MACPs. This gene is widely expressed in many tissues with the greatest abundance in brain and testis. The gene product has an N-terminal hydrophobic domain that is not present in other UCPs. Two splice variants have been found for this gene.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: BMCP-1; Brain mitochondrial carrier protein 1; Mitochondrial uncoupling protein 5; solute carrier family 25 (mitochondrial carrier, brain), member 14; Solute carrier family 25 member 14; UCP 5
基因别名: BMCP1; SLC25A14; UCP5; UCP5L; UCP5S; UNQ791/PRO1682
UniProt ID: (Human) O95258, (Mouse) Q9Z2B2
Entrez Gene ID: (Human) 9016, (Mouse) 20523, (Rat) 85263
