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产品信息
PA5-88033
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant fusion protein containing a sequence corresponding to amino acids 290-573 of human FATP2 (NP_0036362)
偶联物
形式
Liquid
浓度
0.57 mg/mL
纯化类型
Affinity Chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.05% ProClin 300
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Wet ice
RRID
AB_2804604
产品详细信息
Immunogen sequence: TKFSASQFWD DCRKYNVTVI QYIGELLRYL CNSPQKPNDR DHKVRLALGN GLRGDVWRQF VKRFGDICIY EFYAATEGNI GFMNYARKVG AVGRVNYLQK KIITYDLIKY DVEKDEPVRD ENGYCVRVPK GEVGLLVCKI TQLTPFNGYA GAKAQTEKKK LRDVFKKGDL YFNSGDLLMV DHENFIYFHD RVGDTFRWKG ENVATTEVAD TVGLVDFVQE VNVYGVHVPD HEGRIGMASI KMKENHEFDG KKLFQHIADY LPSYARPRFL RIQDTIEITG TFKH
Positive Samples: HepG2; Cellular Location: Endoplasmic reticulum membrane, Multi-pass membrane protein, Peroxisome membrane
靶标信息
The protein encoded by this gene is an isozyme of long-chain fatty-acid-coenzyme A ligase family. Although differing in substrate specificity, subcellular localization, and tissue distribution, all isozymes of this family convert free long-chain fatty acids into fatty acyl-CoA esters, and thereby play a key role in lipid biosynthesis and fatty acid degradation. This isozyme activates long-chain, branched-chain and very-long-chain fatty acids containing 22 or more carbons to their CoA derivatives. It is expressed primarily in liver and kidney, and is present in both endoplasmic reticulum and peroxisomes but not in mitochondria. Its decreased peroxisomal enzyme activity is in part responsible for the biochemical pathology in X-linked adrenoleukodystrophy.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Arachidonate--CoA ligase; FATP-2; Fatty acid transport protein 2; Fatty-acid-coenzyme A ligase, very long-chain 1; Long-chain fatty acid transport protein 2; Long-chain-fatty-acid--CoA ligase; Phytanate--CoA ligase; Slc27a2; solute carrier family 27 (fatty acid transporter), member 2; solute carrier family 27 (fatty acid transporter), member 32; Solute carrier family 27 member 2; THCA-CoA ligase; ve; Very long-chain acyl-CoA synthetase; very long-chain acyl-Coenzyme A dehydrogenase synthase; very long-chain fatty-acid-coenzyme A ligase 1; Very long-chain-fatty-acid-CoA ligase; very-long-chain acyl-CoA synthetase; VLACS; VLCS
基因别名: ACSVL1; FACVL1; FATP2; hFACVL1; HsT17226; SLC27A2; Vlac; VLACS; VLCS
UniProt ID: (Human) O14975, (Rat) P97524, (Mouse) O35488
Entrez Gene ID: (Human) 11001, (Rat) 65192, (Mouse) 26458
long-chain fatty acid-CoA ligase activity
receptor binding
ATP binding
fatty acid transporter activity
enzyme binding
very long-chain fatty acid-CoA ligase activity
phytanate-CoA ligase activity
pristanate-CoA ligase activity
decanoate--CoA ligase activity
protein binding
nucleotide binding
catalytic activity
acyl-CoA ligase activity
succinate-CoA ligase activity
3-oxo-2-(2'-pentenyl)cyclopentane-1-octanoic acid CoA ligase activity
fatty acid ligase activity
ligase activity
3-isopropenyl-6-oxoheptanoyl-CoA synthetase activity
2-oxo-delta3-4,5,5-trimethylcyclopentenylacetyl-CoA synthetase activity
benzoyl acetate-CoA ligase activity
2,4-dichlorobenzoate-CoA ligase activity
pivalate-CoA ligase activity
cyclopropanecarboxylate-CoA ligase activity
adipate-CoA ligase activity
citronellyl-CoA ligase activity
mentha-1,3-dione-CoA ligase activity
thiophene-2-carboxylate-CoA ligase activity
2,4,4-trimethylpentanoate-CoA ligase activity
cis-2-methyl-5-isopropylhexa-2,5-dienoate-CoA ligase activity
trans-2-methyl-5-isopropylhexa-2,5-dienoate-CoA ligase activity
branched-chain acyl-CoA synthetase (ADP-forming) activity
aryl-CoA synthetase (ADP-forming) activity
3-hydroxypropionyl-CoA synthetase activity
perillic acid:CoA ligase (ADP-forming) activity
perillic acid:CoA ligase (AMP-forming) activity
(3R)-3-isopropenyl-6-oxoheptanoate:CoA ligase (ADP-forming) activity
(3R)-3-isopropenyl-6-oxoheptanoate:CoA ligase (AMP-forming) activity
malonyl-CoA synthetase activity
transporter
secondary carrier transporter
fatty acid alpha-oxidation
long-chain fatty acid metabolic process
fatty acid beta-oxidation
bile acid biosynthetic process
fatty acid transport
very long-chain fatty acid catabolic process
long-chain fatty acid import
methyl-branched fatty acid metabolic process
very long-chain fatty acid metabolic process
lipid metabolic process
fatty acid metabolic process
metabolic process
