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Immunogen sequence: RKPISIVKSR LHQNCSEQIK PINDTHSLND TMWCSWAPFD KDNYKE
Highest antigen sequence identity to the following orthologs: Mouse - 83%, Rat - 80%.
The Slc37 gene family consists of four members which have 10-12 predicted transmembrane domains and belong to the sugar-phosphate transporter superfamily. Recent experiments have demonstrated that Slc37A2 is a macrophage-specific gene selectively expressed in obese white adipose tissue. Its transcript is also expressed in spleen and thymus and the cell lines RAW264.7 and THP-1. Compared to wild-type mice, Slc37A2 mRNA is expressed at nine-fold higher levels in abdominal epididymal fat deposits of ob/ob mice, suggesting that it may be required to limit the contribution of macrophages to the inflammatory state present in obesity. Slc37A2 protein is post-translationally modified with the addition of N-linked glycans and migrates as a heterogeneous species of 50-75 kDa.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Glucose-6-phosphate exchanger SLC37A2; solute carrier family 37 (glucose-6-phosphate transporter), member 2; solute carrier family 37 (glycerol-3-phosphate transporter), member 2; Solute carrier family 37 member 2; sugar phosphate exchanger 2
基因别名: pp11662; SLC37A2
UniProt ID: (Human) Q8TED4
Entrez Gene ID: (Human) 219855