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SLC38A3 Antibody (PA5-92228) in WB
Western blot analysis of SLC38A3 in extracts of various cell lines. Samples were incubated with SLC38A3 Polyclonal antibody (Product # PA5-92228) followed by HRP Goat Anti-Rabbit IgG (H+L) secondary antibody at a dilution of 1:10,000. Lysates/proteins: 25 µg per lane. Blocking buffer: 3% nonfat dry milk in TBST.
产品信息
PA5-92228
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant fusion protein containing a sequence corresponding to amino acids 1-65 of human SLC38A3 (NP_0068321)
偶联物
形式
Liquid
浓度
0.28 mg/mL
纯化类型
Affinity Chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.01% thimerosal
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Wet ice
RRID
AB_2806416
产品详细信息
Immunogen sequence: MEAPLQTEMV ELVPNGKHSE GLLPVITPMA GNQRVEDPAR SCMEGKSFLQ KSPSKEPHFT DFEGK; Positive Samples: HeLa, Raji, Mouse brain; Cellular Location: Cell membrane, Multi-pass membrane protein
靶标信息
As a sodium-dependent amino acid/proton antiporter, SLC38A3 mediates electrogenic cotransport of glutamine and sodium ions in exchange for protons. It also recognizes histidine, asparagine and alanine. It may mediate amino acid transport in either direction under physiological conditions and play a role in nitrogen metabolism and synaptic transmission.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: mNAT; N system amino acids transporter NAT-1; N-system amino acid transporter 1; Na(+)-coupled neutral amino acid transporter 3; SLC38A3; slc38a3 {ECO:0000312|RGD:628620}; Sodium-coupled neutral amino acid transporter 3; Solute carrier family 38 member 3; solute carrier family 38, member 3; System N amino acid transporter 1; system N1 amino acid transporter; system N1 Na+ and H+-coupled glutamine transporter
基因别名: 0610012J02Rik; D9Ucla2; G17; mNAT; NAT1; Slc38-3; SLC38A3; SN1; SNAT3
UniProt ID: (Human) Q99624, (Rat) Q9JHZ9, (Mouse) Q9DCP2
Entrez Gene ID: (Human) 10991, (Rat) 252919, (Mouse) 76257
sodium ion transport
amino acid transport
asparagine transport
glutamine transport
brain development
female pregnancy
L-alanine transport
histidine transport
cellular response to potassium ion starvation
positive regulation of transcription from RNA polymerase II promoter in response to acidic pH
L-histidine transmembrane transport
positive regulation of glutamine transport
amino acid transmembrane transport
transport
ion transport
drug transmembrane transport
cation transmembrane transport
L-alpha-amino acid transmembrane transport
