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SLC4A11 Antibody (PA5-90811) in WB
Western blot analysis of SLC4A11 in HepG2 cells. Samples were incubated with SLC4A11 Polyclonal antibody (Product # PA5-90811) using a dilution of 1:2,000, followed by HRP Goat Anti-Rabbit IgG (H+L) at a dilution of 1:10,000. Lysates/proteins: 25 µg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 60s.
产品信息
PA5-90811
产品规格
种属反应
Human,
Mouse
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant fusion protein containing a sequence corresponding to amino acids 1-180 of human SLC4A11 (NP_0011675601)
偶联物
形式
Liquid
浓度
1.6 mg/mL
纯化类型
Affinity Chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.05% ProClin 300
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Wet ice
RRID
AB_2806247
产品详细信息
Positive Samples: 293T, Mouse kidney; Cellular Location: Cell membrane, Membrane, Multi-pass membrane protein
Immunogen sequence: MAAATRRVFH LQPCENSPTM SQNGYFEDSS YYKCDTDDTF EAREEILGDE AFDTANSSIV SGESIRFFVN VNLEMQATNT ENEATSGGCV LLHTSRKYLK LKNFKEEIRA HRDLDGFLAQ ASIVLNETAT SLDNVLRTML RRFARDPDNN EPNCNLDLLM AMLFTDAGAP MRGKVHLLSD
靶标信息
This gene encodes a voltage-regulated, electrogenic sodium-coupled borate cotransporter that is essential for borate homeostasis, cell growth and cell proliferation. Mutations in this gene have been associated with a number of endothelial corneal dystrophies including recessive corneal endothelial dystrophy 2, corneal dystrophy and perceptive deafness, and Fuchs endothelial corneal dystrophy. Multiple transcript variants encoding different isoforms have been described.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: bicarbonate transporter related protein 1; bicarbonate transporter-related protein 1; CDPD; MGC126418; MGC126419; NaBC1; OTTHUMP00000030097; sodium bicarbonate transporter-like protein 11; Sodium borate cotransporter 1; sodium-coupled borate cotransporter 1; Solute carrier family 4 member 11; solute carrier family 4, sodium bicarbonate transporter-like, member 11; solute carrier family 4, sodium borate transporter, member 11
基因别名: AI503023; BTR1; CDPD1; CHED; CHED2; dJ794I6.2; NABC1; SLC4A11
UniProt ID: (Human) Q8NBS3, (Mouse) A2AJN7
Entrez Gene ID: (Human) 83959, (Mouse) 269356
sodium channel activity
inorganic anion exchanger activity
bicarbonate transmembrane transporter activity
hydrogen ion channel activity
symporter activity
anion:anion antiporter activity
borate transmembrane transporter activity
protein dimerization activity
transporter activity
anion transmembrane transporter activity
secondary carrier transporter
