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SLC6A1 Antibody (PA5-85766) in ICC/IF
Immunocytochemistry-Immunofluorescence analysis of SLC6A1 was performed in DIV9 rat E18 primary cortical neuron cells fixed in 4% paraformaldehyde at RT for 15 min. Green: SLC6A1 Polyclonal Antibody (Product # PA5-85766) diluted at 1:500. Red: beta Tubulin 3/ Tuj1, stained by beta Tubulin 3/ Tuj1 antibody. Blue: Fluoroshield with DAPI.
产品信息
PA5-85766
应用
建议稀释比
已发表文章
产品规格
种属反应
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant protein encompassing a sequence within the center region of mouse GABA Transporter 1.
偶联物
形式
Liquid
浓度
1.55 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7, with 20% glycerol
内含物
0.025% ProClin 300
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Wet ice
RRID
AB_2792903
产品详细信息
Keep as concentrated solution.
Predicted reactivity: Human (98%), Mouse (100%), Rat (100%), Xenopus laevis (85%), Rhesus Monkey (98%), Bovine (94%).
Positive Control: rat cerebellum.
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
靶标信息
GAT-1 (SLC6A1) The protein encoded by SLC6A1 is a gamma-aminobutyric acid (GABA) transporter that localizes to the plasma membrane. The encoded protein removes GABA from the synaptic cleft, restoring it to presynaptic terminals.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: GABA T-1; GABA T1; GABA transporter protein; GABAT1; gamma-aminobutyric acid (GABA-A) transporter 1; GAT-1; Sodium- and chloride-dependent GABA transporter 1; solute carrier family 6 (neurotransmitter transporter, GABA), member 1; Solute carrier family 6 member 1
基因别名: A730043E01; GABATHG; GABATR; Gabt; Gabt1; GAT-1; Gat1; Slc6a1; XT-1; Xtrp1
UniProt ID: (Rat) P23978, (Mouse) P31648
Entrez Gene ID: (Rat) 79212, (Mouse) 232333
neurotransmitter transport
learning
response to toxic substance
response to sucrose
response to organic substance
response to organonitrogen compound
response to lead ion
positive regulation of gamma-aminobutyric acid secretion
response to organic cyclic compound
response to purine-containing compound
negative regulation of synaptic transmission, GABAergic
response to estradiol
response to cocaine
protein homooligomerization
response to calcium ion
gamma-aminobutyric acid import
transmembrane transport
amino acid transmembrane transport
transport
sodium ion transmembrane transport
mitophagy in response to mitochondrial depolarization
