Search Thermo Fisher Scientific
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
图: 1 / 6
SLC7A11 Antibody (MA5-44922) in ICC/IF
Immunocytochemistry analysis of xCT in HT-29 cells. Cells were fixed in 4% paraformaldehyde for 30 minutes, permeabilized with 0.1% Triton X-100 in PBS for 15 minutes, and then blocked with 2% BSA for 30 minutes at room temperature. Samples were incubated in xCT Monoclonal antibody (Product # MA5-44922) using a dilution of 1:200 in 2% BSA overnight at 4 followed by Goat Anti-Mouse IgG H&L (iFluor™ 488) secondary antibody at a dilution of 1:1,000. PBS instead of the primary antibody was used as the secondary antibody only control. Nuclear ... View More
产品信息
MA5-44922
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse
宿主/亚型
Mouse
/ IgG2b
Expression System
HEK293 cells
分类
Recombinant Monoclonal
类型
Antibody
克隆号
A7C6-R
抗原
293 cell line overexpressing SLC7A11.
偶联物
形式
Liquid
浓度
1.0 mg/mL
纯化类型
Protein A
保存液
PBS, pH 7.4, with 40% glycerol, 0.1% BSA
内含物
0.05% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
AB_2931378
靶标信息
SLC7A11 (also known as XCT) is a member of a hetromeric, sodium-independent, anionic amino acid transport system. It is highly specific for cysteine and glutamate. SLC7A11 is a mediator of Kaposi sarcoma-associated herpes virus fusion and entry into cells. Increased expression of this protein in primary gliomas is associated with neuronal cell death.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
篇参考文献 (0)
您是否在文献中引用过该产品？请点击下方按钮邮件告知我们。
生物信息学
蛋白别名: Amino acid transport system xc-; Calcium channel blocker resistance protein CCBR1; cysteine/glutamate transporter; Cystine/glutamate transporter; sodium independent anionic amino acid transport system; solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11; Solute carrier family 7 member 11; solute carrier family 7, (cationic amino acid transporter, y+ system) member 11; Subtle gray protein; xCT
基因别名: 9930009M05Rik; AI451155; CCBR1; SLC7A11; sut; xCT
UniProt ID: (Human) Q9UPY5, (Mouse) Q9WTR6
Entrez Gene ID: (Human) 23657, (Mouse) 26570
amino acid transmembrane transport
amino acid transport
response to oxidative stress
brain development
response to toxic substance
response to nicotine
leukocyte migration
lens fiber cell differentiation
platelet aggregation
L-glutamate transmembrane transport
transport
neutral amino acid transport
modified amino acid transport
