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SLC7A5 Antibody (MA5-50500) in ICC/IF
Immunocytochemical analysis of SLC7A5 using SLC7A5 Recombinant Monoclonal Antibody (Product # MA5-50500) in Caco-2 cells at a dilution of 1:500. Cells were fixed in ice-cold MeOH for 5 min. Green: SLC7A5 stained by SLC7A5 antibody (MA5-50500) diluted at 1:500. Blue: Fluoroshield with DAPI.
产品信息
MA5-50500
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
Expression System
HEK293 cells
分类
Recombinant Monoclonal
类型
Antibody
克隆号
HL2353
抗原
Recombinant protein encompassing a sequence within the N-terminus region of human LAT1/SLC7A5. The exact sequence is proprietary.
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Protein A
保存液
PBS
内含物
no preservative
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Wet ice
RRID
AB_3094275
靶标信息
Solute carrier family 7 member 5 also known as large neutral amino acids transporter small subunit 1 is a protein that in humans is encoded by the SLC7A5 gene.It is sodium-independent, high-affinity transport of large neutral amino acids such as phenylalanine, tyrosine, leucine, arginine and tryptophan, when associated with SLC3A2/4F2hc.It involved in cellular amino acid uptake and the transport of L-DOPA across the blood-brain barrier, and that of thyroid hormones triiodothyronine (T3) and thyroxine (T4) across the cell membrane in tissues such as placenta.Acts as an amino acid exchanger and plays a role in neuronal cell proliferation (neurogenesis) in brain.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: 4F2; 4F2 LC; 4F2 light chain; 4F2HC; 4F2LC; 4T2HC; CD98 light chain; CD98HC; E16; hLAT1; Integral membrane protein E16; L-type amino acid transporter 1; large neutral amino acids transporter 1; Large neutral amino acids transporter small subunit 1; LAT-1; LAT1; MDU1; MP hLAT1; NACAE; Protein TA1; sodium-independent neutral amino acid transporter LAT1; solute carrier family 7 (amino acid transporter light chain, L system), member 5; solute carrier family 7 (cationic amino acid transporter, y+ system), member 5; Solute carrier family 7 member 5; tumor-associated protein 1; y+ system cationic amino acid transporter
基因别名: 4F2LC; CD98; CD98LC; D0H16S474E; D16S469E; E16; hLAT1; LAT1; MPE16; SLC7A5; TA1
UniProt ID: (Human) Q01650, (Mouse) Q9Z127, (Rat) Q63016
Entrez Gene ID: (Human) 8140, (Mouse) 20539, (Rat) 50719
amino acid transmembrane transporter activity
neutral amino acid transmembrane transporter activity
L-amino acid transmembrane transporter activity
antiporter activity
peptide antigen binding
L-leucine transmembrane transporter activity
L-phenylalanine transmembrane transporter activity
L-tryptophan transmembrane transporter activity
transporter
cellular amino acid metabolic process
transport
amino acid transport
nervous system development
neutral amino acid transport
L-amino acid transport
cell differentiation
leukocyte migration
L-alpha-amino acid transmembrane transport
amino acid transmembrane transport
multicellular organism development
leucine transport
phenylalanine transport
tryptophan transport
cation transmembrane transport
